CV Lattes
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Biologia e Quimica from Universidade Federal de Tomsk (1978), master's at Biologia e Quimica from Universidade Federal de Tomsk (1981) and ph.d. at Citogenética from Instituto de Citologia e Genética (1989). Has experience in Genetics, acting on the following subjects: differentiation, diptera, adult stem cells, chromosome polymorphism and células embrionárias tronco. (Source: Lattes Curriculum)
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Successful drug development requires a disease target that plays a vital role in the causation and/or progression of the disease phenotype and that can be modulated with a drug molecule. In other words, therapeutically relevant targets are both “disease-modifying” and “druggable”. It has been estimated that around 10% of the entire human genome is involved in disease onset or progression,…
Recent findings on heterogeneity, flexibility and plasticity of stem cells are challenging the traditional concept of stem cells as pre-programmed entities. The concept of self-organizing systems offers an alternative, more elegant and comprehensive explanation for the experimental data. In recent decades, biological studies of stem cells have evolved a broad spectrum of phenomena, rangin…
The aim of the Interinstitutional Center for Applied Toxinology is to establish a world-class center for research into natural toxins. The Center will develop the study of toxins with the aim to investigate their potential therapeutic use, to foster contacts between science and industry and to raise the level of scientific human resources. The Institute Butantan with its history and tradi…
Osteoclasts acts in bones maintenance, repair and remodeling. Bone diseases such as Osteoporosis and Rheumatoid Arthritis have increased osteoclastogenesis, a devastating effect for bone loss. Therefore, there is a critical importance in the study of specific proteins or signaling pathways in the process of osteoclast differentiation. This process will be studied in a model of Peripheral …
Crotamine is a basic polypeptide found in the venom of Crotalus durissus terrificus. Crotamine is of great biotechnological interest since it is classified as a cell penetrating peptide (CPP), this feature is directed mainly to cells in proliferation, what proposes that tumour cells could be a target of it. Recently it was addressed in the literature, a new activity of crotamine in the st…
Aplastic anemia is a disease characterized by a partial or complete bone marrow failure, through a pluripotent Stem Cell Hematopoietic (HSC) assault, leading to decline and even absence of bone marrow. The treatment is typically given by HSC transplantation and administration of immunosuppressive drugs, but these processes are restricted since the necessity of cell compatibility to the ef…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 5 / 2 | Completed research grants |
| 14 / 9 | Completed scholarships in Brazil |
| 20 / 12 | All research grants and scholarships |
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