Abstract
Acute stress suppresses pain by activating brain pathways that engage opioid and non-opioid mechanisms. Stress-induced analgesia (SIA) can be induced by various stressors, e.g. the social defeat. Nociceptive tests are often used to assess this antinociception, among them stands out the tail-flick test, which consist in a phasic pain test. The SIA is, at least partially, modulated by endov…