Clovis Ryuichi Nakaie

• Abstract

  Five sub-lines of research make up this project, a part strongly supported by improvements and technological innovations in the complex method of chemical synthesis of peptides (natural or not), carried out in polymers. This method, called solid-phase peptide synthesis (SPFS), winner of the 1984 Nobel Prize in Chemistry (Bruce R. Merrifield, Rockefeller University), has been investigated …

  Synthesis and structural investigation of peptides and polymers: from innovation in the synthesis method to the study of some physiological relevant peptides, AP.R

• Abstract

  Five research sub-topics make up this project based heavily on improvements and technological innovations in the complex method of chemical synthesis of peptides made in polymers. This method, known as solid phase synthesis (SPFS), winner of the Nobel Prize in Chemistry in 1984, has been investigated by us at different points in its experimental strategy, allowing us for decades to propos…

  Synthetic and structural studies of peptide and polymers: from the improvement of the synthesis methodology and the search for peptide derivatives for biotechnological applications, AP.R

• Abstract

  SUMMARYInitially, we will proceed with our continuous efforts to improve the complex methodology of peptide synthesis performed on resins. Emphasis will be given to the strategy of development of novel resins but now, extending this approach also to the copolymer necessary for the synthesis of these resins. We are going also to evaluate the possibility of applying these materials as fixed…

  Synthesis and structural investigation of peptides and polymers: from improvement of the synthesis methodology to the study of some physiologically relevant peptídes., AP.R

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