- Research Grants
Luciano Neder Serafini in research grants and scholarships supported by FAPESP.
In the past few years, several studies have been addressed the molecular mechanisms related to glioma progression. However, the prognosis of patients with high-grade gliomas remains dismal. The study of new molecular markers enrolled in the tumor progression has been created new lines of research, mainly those related to genetic modulation or gene silencing. MicroRNAs are a large tiny r...
Apoptosis is the mechanism of cell death which promotes the removal of cells in normal tissue and is fundamental during development. In tumors, it can be the result of extra cellular stimulus or of characteristics intrinsic to the cells, depending on the expression of oncogenes. Alterations in genes which codify endonuclear caspases, receptors of cell death and mitochondrial proteins ar...
Malignant gliomas are the most common and lethal primary human brain tumors. Due to the infiltrative growth of these tumors, surgical cure is not a viable option and the majority of these tumors are resistant to standard radiotherapy and chemotherapeutic approaches. A key factor contributing to the refractory nature of malignant gliomas is tumor heterogeneity. The WHO classification sys...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|