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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Colômbia
Norberto Garcia-Cairasco is a Biology Undergraduate from the Science Faculty at the Universidad Del Valle (1976), at Cali Colombia. He got his Master (1982) and his PhD (1984) degrees in Physiology (Neurophysiology) at the Ribeirão Preto School of Medicine at the Ribeirão Preto, São Paulo, Brazil. He did his Post-Doctoral training (1988-1990) at the Neurology Department of the Duke Medical Center at Duke University, North Carolina,USA, under the supervision of James O. McNamara. In 2011 he was promoted to the Category of Associate Professor (Livre Docente). Since November 2013 was promoted to the Category of Full Professor (MS-6, em R.D.I.D.P), at the Departament of Physiology at the Ribeirão School of Medicine of the UNiversity of São Paulo. He is currently Adviser at the Graduate Programs (PROEX-CAPES) in Physiology and Neurology/Neurosciencie at the same Medical School and is the Coordinator of the Graduate Program in Physiology. He was elected Senior Member of the Neurobiology Commission of the International League Against Epilepsy (2013-2017) and is Member of the Editorial Board of the Journal Epilepsy Behavior, acting as Guest-Editor of the Supplement "International Symposium NEWroscience 2008. Contemporary Neuroscience, Epilepsy and the Arts (published in 2009; 11 Articles)) and of the Special Issue "International Symposium NEWroscience 2013. Epilepsies: Complexity and Comorbidities" (published in 2014; 23 Articles). He has experience in the Area of Physiology,with emphasis in Neurophysiology, acting mainly and in an integrated manner in the following themes: Behavioral (Quantitative Neuroethology), Eletrophysiological, Cellular and Molecular Characterization of Alterations of the Motor Control, among them the Epilepsies (Basic and Clinic), Experimental models of Obsessive-Compulsive Disorders and of Parkinson Disease.In addition, he studies Plasticity of the Auditory System and Sensory-Motor and Sensory-Limbic Integration. The above research lines have evolved to Studies of Systems Complexity in the Neuroscience, thanks to collaborative Projects in Computational Neuroscience. He also coordinates and executes activities in the Neuroscience Arts interface and is a Member, invited by the Brazilian Society for Neuroscience and Behavior (SBNeC) of the National Commission of the "Semana Nacional do Cérebro" the brazilian counterpart of the Worldwide known "Brain Awareness Week" (Semana Mundial do Cérebro), which internationally is supported by the Dana Foundation for Brain Initiatives, the Society for Neuroscience (SfN) and the International Brain Research Organization (IBRO). NGC is a Member of both SfN and IBRO. (Source: Lattes Curriculum)
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Alzheimer's disease (AD), the most common type of dementia and the fourth leading cause of disability among people aged 75 and over, is a progressive neurodegenerative condition. It impairs memory and language and causes behavioral/psychiatric changes. Evidence from the literature and from the Laboratory of Neurophysiology and Experimental Neuroethology (LNNE), with experience in epilepsy…
This project attempts to enhance the cooperation of two laboratories that work with two models of experimental epilepsy (audiogenic seizures), strengthening collaboration between researchers, encouraging visiting researchers to share knowledge, resources and techniques in which each laboratory has more expertise. All this leads to coordinate a research project that helps to determine the …
In the current project we initially make an introduction to the history of the Wistar Audiogenic Rat (WAR) strain, developed by our group since the 1990s, and of the research with the epilepsies and neuropsyquiatric comorbidities involving this model. We introduce immediately after all the justification to search for novel antiepileptogenic and neuroprotection alternatives, because a sign…
(Only some records are available in English at this moment)
Epilepsy is a serious neurological disease that is quite prevalent in the population, but its currently available treatments (pharmacological or surgical) are refractory in many patients, which raises the need to explore new targets. Historically, electrical stimulation of the cerebellum achieved promising results in the second half of the last century, but these were often inconsistent b…
Epilepsy is a serious illness consisting of seizures resulting from hypersynchronism and hyperexcitability in the brain. In certain epilepsies, the involvement of limbic structures such as the hippocampus stands out, especially susceptible to seizures. On the other hand, studies indicate that the substantia nigra pars compacta (SNpc) is a structure possibly involved in the suppression of …
Alzheimer's Disease (AD), the most common form of dementia, is a highly prevalent progressive neurodegenerative disorder. AD's main symptoms are cognitive decline and personality alterations, including memory loss and mental confusion. The main pathophysiological biomarkers of AD are amyloid-beta (A²) plaque and neurofibrillary tangles resultant of tau protein hyperfosforilation. Suggesti…
(Only some records are available in English at this moment)
Stressful situations during early life (early life stress, ELS), such as physical, sexual and emotional abuse or neglect, are associated with a higher risk of developing psychopathologies in adult life, like posttraumatic stress disorder (PTSD), which is triggered by a traumatic event, and is characterized by inappropriate processing of emotional information resulting in anxiety, revival,…
Adolescence is a developmental period associated with continued organization of neural circuitry regulating emotional behaviors. Recent works have shown that during adolescence suppression of contextual fear retrieval occurs. Rather than a failure to learn the association, in adolescent mice the context was temporarily incapable of eliciting a fear response. The ability to use context to …
Epilepsy affects about 1% of world population according to WHO, and temporal lobe epilepsy (TLE) is the most common form of epilepsy in adults (Pitkänen, 2007). Febrile seizures (FS) are the most frequent type of convulsions in infants and young children, occurring in 2-6% of children (Nelson & Ellenberg 1976; Stafstrom, 2002). Long duration FS have been associated with subsequent TLE as …
| 1 / 1 | Ongoing grants |
| 23 / 14 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 30 / 17 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 58 / 36 | All research grants and scholarships |
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