CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina (FMB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Degree in Biochemistry Pharmacy from the University of Ribeirão Preto (1992), Master of Pathology (2000) and PhD in Pathology (2006) from the Universidade Estadual Paulista Julio de Mesquita Filho and Postdoctoral at the Human Nutrition Research Center (HNRC) at the University of Tufts in Boston, MA on oxidative stress area (2008 to 2010). Currently Permanent Professor of the Graduate Program in Pathology, School of Medicine of Botucatu, UNESP and Academic Support Assistant at the Experimental Unit of the Faculty of Medicine (UNIPEX) - Botucatu, UNESP. It has experience in biochemistry, acting on the following topics: oxidative and inflammatory stress, micronutrients and chromatography of high efficiency (HPLC) and antioxidants and bioactive compounds. (Source: Lattes Curriculum)
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Obesity triggers inflammation and oxidative stress, both of which are involved in the pathogenesis of various organs. For this reason, natural compounds with anti-inflammatory and antioxidant action have been the subject of research, since these substances can be easily implemented in the food routine. Bergamot (Citrus bergamia) is a citrus fruit that has an antioxidant and anti-inflammat…
Cardiorenal metabolic syndrome (CRMS) is a pathological condition associated with the development of cardiac and renal dysfunction due to obesity and associated complications, in which oxidative stress plays an important role in triggering the carbonylation of proteins The gamma-oryzanol (³Oz), the main phytosterol present in rice grains, has demonstrated potential antiadipogenic, hypocho…
Obesity is associated with several comorbidities such as dyslipidemia, hypertriglyceridemia, insulin resistance (IR) and diabetes mellitus type 2. Currently the literature reports that these comorbidities are directly related to oxidative stress and inflammation, situations that trigger an imbalance in production adipokine, or increase of proinflammatory cytokines and decrease adiponectin…
(Only some records are available in English at this moment)
High sugar and saturated fats diets are associated with metabolic complications, systemic inflammation, and overweight, which promote the development of diseases such as dyslipidemia and chronic kidney disease (CKD). Dyslipidemia, characterized by alterations in plasma lipid levels, results in oxidative stress and inflammation, impacting vital organs, including the kidneys. Bioactive comp…
The high consumption of foods rich in saturated fats and simple sugars are associated with the incidence of metabolic disorders, including obesity. This disease compromises the striated skeletal muscle, leading to several losses, among them the uptake of glucose. Citrus bergamia, known as bergamot, is rich in bioactive compounds with antioxidant and anti-inflammatory capacity. This fruit,…
Bergamot (Citrus bergamia) has been studied as a therapeutic strategy to combat metabolic changes due to its antioxidant activity. Cardiorenal Metabolic Syndrome (CRMS) is a disease resulting from kidney and heart dysfunction resulting from metabolic changes and oxidative stress. The objective of this study is to investigate the action of Citrus bergamia byproduct on the manifestation of …
(Only some records are available in English at this moment)
The literature reports that the consumption of western diet can trigger damage to skeletal muscles by several metabolic pathways. To preserve skeletal muscle tissue, the use of bioactive compounds has been tested. It is described that the Gamma-Oryzanol (³Oz ) has great influence on the mechanisms involved in skeletal muscle metabolism. Even though these reports are already established, s…
Cancer is a disease of altered signaling and metabolism derived from abnormal and accelerated cell growth, which can begin in any organ or tissue. Doxorubicin (DOX) isa chemotherapy drug from the anthracycline group widely used to treat neoplasms. Although it is effective, it is not selective and its toxic and side effects are clinically apparent, such as nausea, vomiting, hypersensitivit…
Obesity, in the last decades, has been pointed out as a public health problem for causing comorbidities that compromise the cardiovascular system. Among the pathophysiological mechanisms is the chronic low-grade inflammation resulting from the predominance of the M1-type macrophage profile. Therapeutic strategies have been investigated in an attempt to relieve these comorbidities so that …
(Only some records are available in English at this moment)
Obesity is a multifactorial metabolic disorder caused by the excessive consumption of fatsand sugars. This condition leads to an increase in adipose tissue, triggering systemicinflammatory and oxidative states. It can affect various tissues, contributing to thedevelopment of several diseases. Given these challenges, bioactive compounds from citrusfruits, such as flavonoids and polyphenols…
The literature reports that the consumption of western diet can trigger damage to skeletal muscles by several metabolic pathways. To preserve skeletal muscle tissue, the useof bioactive compounds has been tested. It is described that the Gamma- Oryzanol (³Oz) has great influence on the mechanisms involved in skeletal muscle metabolism. Even though these reports are already established, st…
The current nutritional transition process added to a sedentary lifestyle has been associated with the remodeling and expansion of adipose tissue, so called obesity. The various substances produced by this tissue are called adipokines, and include hormones and other proteins such as cytokines, in this case called adipocytokines, among them are interleukin-6 (IL-6), tumor necrosis factor-±…
| 12 / 9 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 26 / 26 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 48 / 45 | All research grants and scholarships |
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