bachelor's at Farmácia from Universidade Metodista de Piracicaba (2002), master's at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2004) and doctorate at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2007). Has experience in Pharmacy, focusing on Pharmacotechnie, acting on the following subjects: estágio supervisionado, sistemas líquido-cristalinos, assessoria científica, cafeína and estabilidade físico-química. (Source: Lattes Curriculum)
| Articles published in Pesquisa para Inovação FAPESP about the researcher: |
| Scientists use chitosan to develop more stable antioxidant microparticles for cosmetics |
| News published in Agência FAPESP Newsletter about the researcher |
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Glioblastoma multiforme (GBM) is the most aggressive and prevalent variation of glioma. The first choice treatment is temozolamide (TMZ), an alkylating agent administered orally or intravenously. However, the drug has some limitations, such as the difficulty in crossing the blood-brain barrier (BBB) and the cellular efflux mechanism resistance. As a consequence, the survival rate of pati…
Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Current anticancer therapies often demonstrate reduced safety and efficacy, so the development of new therapeutic approaches to cancer has been the goal of much research. In this context, activation of the host immune system against tumor antigens has received special attention as it represents a significantly safer and more effective alternative than chemotherapy and other conventional c…
(Only some records are available in English at this moment)
Glioblastoma multiforme (GBM) is the most prevalent and aggressive neoplasm of the Central Nervous System (CNS). Cannabis sativa L. oil (OC) has emerged as a potential alternative for GBM treatment, as the tumor cells express higher levels of cannabinoid receptors, which are associated with selective apoptosis and cell cycle disruption in neoplastic cells. However, OC faces physical and c…
The treatment of colorectal cancer (CC), although effective, is associated with numerous limitations, such as the lack of specificity/selectivity of drugs, leading to systemic side effects. Curcumin (CUR) has been the subject of several researches for the treatment of different types of cancers due to its antitumor activity; however, it has low aqueous solubility, low stability, and probl…
Inflammatory bowel diseases (IBD) is a set of autoimmune diseases that cause intestinal inflammation and whose main entities are Crohn's disease and ulcerative colitis. As an imbalance in the gut microbiome can lead to the development of various intestinal diseases, the use of prebiotics, probiotics, and post-biotics to alter the gut microbiome has aroused recent interest. Postbiotics inc…
(Only some records are available in English at this moment)
Helicobacter pylori colonizes the gastric epithelium and is often associated with infections such as gastric disorders, gastritis, ulcers, mucosa-associated lymphoid tissue (MALT lymphoma) and even gastric adenocarcinomas. The difficulties faced in treating infections caused by this bacterium drive the search for new alternatives, such as natural products with antimicrobial activity, such…
Glioblastoma Multiforme (GBM) is the most incident and most aggressive neoplasm of the Central Nervous System (CNS). Temozolamide (TMZ), the drug of choice for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical and chemical limitatio…
Prostate Cancer is the second Cancer with the highest mortality in Brazil, affecting mainly men in old age. The recommended treatment varies according to the tumor stage, and it is possible to choose therapies alone or in combination. Among therapies, chemotherapeutic agents are widely used; however, the tumor may show resistance causing the efflux of drugs from the cell, in addition to g…
(Only some records are available in English at this moment)
Ulcerative colitis (UC) and Crohn's disease (CD) are inflammatory bowel diseases (IBD) characterized by chronic inflammation without cure in the gastrointestinal tract (GIT), mainly in the colon. Treatment focuses on controlling the disease, preventing recurrence, and improving the patient's quality of life. Mesalazine (MLZ) is the drug of first choice for the treatment of IBD but has lim…
Glioblastoma multiforme (GBM) is the most frequent and most aggressive Central Nervous System (CNS) cancer. Temozolomide (TMZ), the first-line drug for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical-chemical limitations that hind…
Curcumin is a polyphenol obtained from Curcuma longa L. It has shown antitumor activity in in vitro assays against different prostate cancer strains. However, presents limitations inherent to hydrophobicity and low bioavailability. In this way, curcumin will be incorporated into polymeric nanoparticles using D-±-tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant, due to …
(Only some records are available in English at this moment)
Vulvovaginal candidiasis currently represents a major public health challenge due to its high incidence and recurrences reports. These challenges may be due to host-related factors, such as compromised immune system, or pathogen-related factors, including resistance to antifungal agents, and making necessary to study new treatment alternatives, e.g., the use of natural origin substances s…
Helicobacter pylori is a microorganism that is directly related to severe clinical conditions of chronic gastritis, peptic ulcer, and gastric cancer. The virulence factors and the ability of these bacteria to form biofilms increase the resistance to conventional antimicrobials. In this sense, there is a growing interest in the search for new substances, among them of natural origin, as we…
Climate change, ineffective diagnoses, and uncontrolled use of antibiotics are factors that justify the emergence of new species of microorganisms with a high capacity for dissemination and mortality. This is the example of Candida auris, a yeast that appeared in Japan in 2009 and which today is a matter of worldwide concern due to its high resistance to therapy and mortality worldwide. A…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 10 / 8 | Completed research grants |
| 10 / 10 | Ongoing scholarships in Brazil |
| 44 / 44 | Completed scholarships in Brazil |
| 5 / 5 | Ongoing scholarships abroad |
| 23 / 23 | Completed scholarships abroad |
| 94 / 92 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID