CV Lattes
ORCID
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Colombo received his medical degree from the Escola Paulista de Medicina, Federal University of São Paulo, Brazil, where he also continued his residency training in Internal Medicine and Infectious Diseases (1983-1986). He completed his fellowship in Medical Mycology at the University of Texas Health Science Centre at San Antonio, Texas, USA (1992-1994). He is currently a Professor of Medicine in the Federal University of São Paulo, and he serves as a consultant on Medical Mycology for several institutions in Brazil and Latin America.He was the Vice-Chancellor of Graduate Students and Research of the Federal University of São Paulo between February 2009 and February 2012. Dr Colombo was a senior advisor for Leading International Fungal Education (LIFE, 2013-2021), as we as integrated the International Council Member of the International Immunocompromised Host Society (2016-2921). Currently he is Senior Advisor for the Global Action for Fungal Infections (GAFFI, 2013 - present) and convenor of INFOCUS LATAM ISHAM Working Group (2019-present). Recently, he was nominated fellow of the European Confederation of Medical Mycology (2018) and Permanent Member of the Brazilian Academy of Science (2020).Dr. Colombo has authored and co-authored a total of 231 publications in peer-reviewed journals, accumulating more than 17,300 citations (H index 69, google academic). He has organized several multicentre surveillance studies to characterize the epidemiology and clinical aspects of Candida spp. Aspergillus spp. and Trichosporon invasive infections. In addition, he coordinated and/or participated of several studies to characterize the burden of antifungal resistance and molecular mechanisms involved. Finally, he coordinated or co-authored several guidelines for the clinical management of fungal infections that were organized by local and international academic and/or medical societies. (Source: Lattes Curriculum)
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Antimicrobial resistance (AMR) has been considered one of the main threats to the human race in the 21st century. We are facing an unstoppable fast-forward instance of Darwinian adaptation through natural selection, in which microbes are constantly evolving to survive antimicrobials. As part of their natural behavior, they adapt continuously. They will succeed unless we develop effective …
Antimicrobial resistance (AMR) has been considered one of the main threats to the human race in the 21st century. We are facing an unstoppable fast-forward instance of Darwinian adaptation through natural selection, in which microbes are constantly evolving to survive antimicrobials. As part of their natural behavior, they adapt continuously. They will succeed unless we develop effective …
Antimicrobial resistance (AMR) has been considered one of the main threats to the human race in the 21st century. We are facing an unstoppable fast-forward instance of Darwinian adaptation through natural selection, in which microbes are constantly evolving to survive antimicrobials. As part of their natural behavior, they adapt continuously. They will succeed unless we develop effective …
Bloodstream Infection (BSI) caused by Candida species is a public health problem worldwide, particularly in Brazil where besides exhibiting high incidence rates, this infection presents crude mortality rates ranging between 50 and 70%. Expanding our horizons of understanding of aspects related to the epidemiology and pathogenesis of these infections, including those caused by emerging pat…
Aspergillus fumigatus is a human fungal pathogen able to cause invasive aspergillosis (IA) associated with high mortality rates in immunocompromised patients and chronic pulmonary aspergillosis (CPA) in immunocompetent individuais with previous pulmonary lesions. Although Brazil is an endemic country for tuberculosis, the main underlying condition associated with CPA, little is known abou…
Invasive aspergillosis (IA) is major cause of morbidity and mortality in profoundly immunocompromised patients. Although many species of Aspergillus have been isolated in nature, A. fumigatus is the primary causative agent of human infections. Once the conidia reach the alveoli, they germinate and produce hyphae that invade the pulmonary tissue. These hyphae have a tropism for blood vesse…
(Only some records are available in English at this moment)
Wickerhamomyces anomalus (syn. Hansenula anomala, Pichia anomala,Candida pelliculosa) is a yeast widely distributed in the environment, beingoften isolated from various sources such as soil, wheat and soybean grains, juicesfruits, insects and humans. In addition to its important role in the food industry,especially in the production and improvement of wine quality, W. anomalusis also reco…
Candidozyma auris is an emerging yeast species with significant public health impact due to its ability to cause outbreaks of invasive infections and its potential to develop multidrug resistance to antifungal treatments. Cdz. auris is not part of the native microbiota of the population; it is an opportunistic microorganism associated with invasive infections in patients with degenerative…
C. parapsilosis is a leading cause of invasive candidiasis, particularly in Latin America, Southern Europe, and Asia, with an increasing prevalence of strains resistant to fluconazole and echinocandins. The study seeks to clarify the controversial relationship between antifungal resistance and virulence, as previous research has shown conflicting results among different Candida species. S…
(Only some records are available in English at this moment)
In recent decades, tertiary hospitals in various regions of the world have faced a significant increase in cases of invasive infections caused by Candida spp. These infections have high rates of morbidity and mortality, and early identification of affected patients often fails. As a result, prophylactic and empirical antifungal therapeutic practices have been increasingly employed. Howeve…
In recent decades, tertiary hospitals in various regions of the world have faced a significant increase in cases of invasive infections caused by Candida spp. These infections have high rates of morbidity and mortality, and early identification of affected patients often fails. As a result, prophylactic and empirical antifungal therapeutic practices have been increasingly employed. Howeve…
Soil is a highly variable ecosystem, dependent on several factors, such as climatic seasonality, which allow its microbial diversification over time. This ecosystem is probably the largest reservoir of antimicrobial resistance genes and the source of its diversity, due to the enormous density of microbial species that reside there. The spread of antimicrobial-resistant pathogens in the ho…
(Only some records are available in English at this moment)
Although candidemia is a concern worldwide, the incidence and mortality rates are particularly staggering in Brazil. According to several authors, for every 1,000 hospital admission in tertiary care Brazilian hospitals, up to 6 patients will develop candidemia and half of them will die from this infection during their hospital admission. Clearly, the management of invasive candidiasis is …
Trichosporon species are yeast-like fungi that have been reported as the second/third most common cause of fungemia in patients with hematological malignancies. Despite the large intraspecific diversity already described for T. asahii (15 genotypes), and T. faecale (3 genotypes), the biological relevance of these genotypes in the human infections is still unclear. Based on the molecular c…
Candida albicans remains the most prevalent species in human superficial and invasive Candida infections, although there is concern over the increasing rates of non-C. albicans infections worldwide. C. parapsilosis is the second Candida species most frequently isolated from blood cultures in South America and in some European countries. Since 2005, when this taxon has been considered a co…
| 3 / 3 | Ongoing grants |
| 18 / 8 | Completed research grants |
| 10 / 10 | Ongoing scholarships in Brazil |
| 28 / 18 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 62 / 42 | All research grants and scholarships |
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