Arnaldo Lopes Colombo
CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Medicina from Universidade Federal de São Paulo (1983), master's at Infectious and Parasitic Illnesses from Universidade Federal de São Paulo (1989) and ph.d. at Doenças Infecciosas e Parasitárias from University of Texas System (1994). Has experience in Medicine, focusing on Infectious and Parasitic Illnesses, acting on the following subjects: candidemia, antifúngicos, infecção hospitalar, candida spp and aids. (Source: Lattes Curriculum)
- Multidisciplinary and international network to characterize microbiological aspects and natural history of invasive fungal infections due Candida spp, AP.TEM
Abstract
Bloodstream Infection (BSI) caused by Candida species is a public health problem worldwide, particularly in Brazil where besides exhibiting high incidence rates, this infection presents crude mortality rates ranging between 50 and 70%. Expanding our horizons of understanding of aspects related to the epidemiology and pathogenesis of these infections, including those caused by emerging p...
- Pulmonary Aspergillosis and correlation between clinical forms and differential expression of virulence attributes in Aspergillus fumigatus, AP.R
Abstract
Aspergillus fumigatus is a human fungal pathogen able to cause invasive aspergillosis (IA) associated with high mortality rates in immunocompromised patients and chronic pulmonary aspergillosis (CPA) in immunocompetent individuais with previous pulmonary lesions. Although Brazil is an endemic country for tuberculosis, the main underlying condition associated with CPA, little is known ab...
- Evaluation of the anti-tumour and angiogenic activity of the Aspergillus fumigatus secretome, AP.R
Abstract
Invasive aspergillosis (IA) is major cause of morbidity and mortality in profoundly immunocompromised patients. Although many species of Aspergillus have been isolated in nature, A. fumigatus is the primary causative agent of human infections. Once the conidia reach the alveoli, they germinate and produce hyphae that invade the pulmonary tissue. These hyphae have a tropism for blood ves...
- Candida parapsilosis complex: epidemiological peculiarities, virulence and mechanisms of antifungal resistance, AP.R
Abstract
Candida albicans remains the most prevalent species in human superficial and invasive Candida infections, although there is concern over the increasing rates of non-C. albicans infections worldwide. C. parapsilosis is the second Candida species most frequently isolated from blood cultures in South America and in some European countries, such as Spain and Italy. Since 2005, when this tax...
(Only some records are available in English at this moment)
- Investigation of the virulence and immune response against Candida auris using alternative model Caenorhabditis elegans, BP.PD
Abstract
Fungi are widely distributed around the world and many have the ability to colonize the skin and mucous membranes of the human host, transitioning from the colonizing agent to the infecting agent in dependence on standard changes in the host's immune response, as well as exposure to antibiotics, immunosuppressant, or invasive medical procedures. Candida spp. Is the most frequent etiolog...
- Evaluation of the anti-tumour and angiogenic activity of the Aspergillus fumigatus secretome, BP.DR
Abstract
Invasive aspergillosis (IA) is major cause of morbidity and mortality in profoundly immunocompromised patients. Although many species of Aspergillus have been isolated in nature, A. fumigatus is the primary causative agent of human infections. Once the conidia reach the alveoli, they germinate and produce hyphae that invade the pulmonary tissue. These hyphae have a tropism for blood v...
- Prevalence of Aspergillus species from clinical/environmental samples and analyze of its susceptibility profile to six antifungal, BP.MS
Abstract
Currently, species of Aspergillus genera are responsible by the second cause of invasive fungal infection in tertiary hospital. In the clinical practice, those infections are difficult to diagnostic and the delayed treatment is very frequent. Few medical centers have the capacity to perform the accurate identification of species in this genus of fungi. The resistance cases to antifungal...
- Candida parapsilosis complex: epidemiological peculiarities, virulence and mechanisms of antifungal resistance, BP.DR
Abstract
Candida albicans remains the most prevalent species in human superficial and invasive Candida infections, although there is concern over the increasing rates of non-C. albicans infections worldwide. C. parapsilosis is the second Candida species most frequently isolated from blood cultures in South America and in some European countries, such as Spain and Italy. Since 2005, when this tax...
(Only some records are available in English at this moment)
- Pathogenicity analysis of C. parapsilosis species complex in experimental models of invertebrates, BE.EP.DR
Abstract
Candida albicans remains the most prevalent species in human superficial and invasive Candida infections, although there is concern over the increasing rates of non-C. albicans infections worldwide. C. parapsilosis is the second Candida species most frequently isolated from blood cultures in South America and in some European countries. Since 2005, when this taxon has been considered a ...
*Updated May 18, 2019
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 28 |
| Citations | 968 |
| Cit./Article | 34.6 |
| Data from Web of Science | |
CHAVES, GUILHERME MARANHAO; SANTOS, FERNANDA PAHIM; COLOMBO, ARNALDO LOPES. The persistence of multifocal colonisation by a single ABC genotype of Candida albicans may predict the transition from commensalism to infection. Memórias do Instituto Oswaldo Cruz, v. 107, n. 2, p. 198-204, MAR 2012. Web of Science Citations: 8. (07/05880-8)
CHAVES, GUILHERME M.; TERCARIOLI, GISELA R.; PADOVAN, ANA CAROLINA B.; ROSAS, ROBERT C.; FERREIRA, RENATA C.; MELO, ANALY S. A.; COLOMBO, ARNALDO L.. Candida mesorugosa sp nov., a novel yeast species similar to Candida rugosa, isolated from a tertiary hospital in Brazil. Medical Mycology, v. 51, n. 3, p. 231-242, APR 2013. Web of Science Citations: 13. (07/08575-1, 07/05880-8)
GONCALVES, SARAH S.; STCHIGEL, ALBERTO M.; CANO, JOSEP; GUARRO, JOSEP; COLOMBO, ARNALDO L.. In Vitro Antifungal Susceptibility of Clinically Relevant Species Belonging to Aspergillus Section Flavi. Antimicrobial Agents and Chemotherapy, v. 57, n. 4, p. 1944-1947, APR 2013. Web of Science Citations: 19. (12/01134-8)
COLOMBO, ARNALDO L.; PADOVAN, ANA CAROLINA B.; CHAVES, GUILHERME M.. Current Knowledge of Trichosporon spp. and Trichosporonosis. CLINICAL MICROBIOLOGY REVIEWS, v. 24, n. 4, p. 682+, OCT 2011. Web of Science Citations: 157. (07/08575-1, 05/02006-0)
BARBOSA PADOVAN, ANA CAROLINA; DE AZEVEDO MELO, ANALY SALLES; COLOMBO, ARNALDO LOPES. Systematic review and new insights into the molecular characterization of the Candida rugosa species complex. Fungal Genetics and Biology, v. 61, p. 33-41, DEC 2013. Web of Science Citations: 12. (09/10155-6, 07/08575-1)
CALVO, BELINDA; MELO, ANALY S. A.; PEROZO-MENA, ARMINDO; HERNANDEZ, MARTIN; FRANCISCO, ELAINE CRISTINA; HAGEN, FERRY; MEIS, JACQUES F.; COLOMBO, ARNALDO LOPES. First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia. Journal of Infection, v. 73, n. 4, p. 369-374, OCT 2016. Web of Science Citations: 110. (12/04767-1)
GONCALVES, SARAH SANTOS; REMONDI SOUZA, ANA CAROLINA; CHOWDHARY, ANURADHA; MEIS, JACQUES F.; COLOMBO, ARNALDO LOPES. Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus. MYCOSES, v. 59, n. 4, p. 198-219, APR 2016. Web of Science Citations: 48. (12/04769-4, 12/04767-1)
SOUZA, ANA CAROLINA R.; FUCHS, BETH BURGWYN; PINHATI, HENRIQUE M. S.; SIQUEIRA, RICARDO A.; HAGEN, FERRY; MEIS, JACQUES F.; MYLONAKIS, ELEFTHERIOS; COLOMBO, ARNALDO L.. Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms and In Vivo Impact in Infected Galleria mellonella Larvae. Antimicrobial Agents and Chemotherapy, v. 59, n. 10, p. 6581-6587, OCT 2015. Web of Science Citations: 35. (12/04769-4, 13/07405-6, 12/04767-1)
IRINYI, LASZLO; SERENA, CAROLINA; GARCIA-HERMOSO, DEA; ARABATZIS, MICHAEL; DESNOS-OLLIVIER, MARIE; VU, DUONG; CARDINALI, GIANLUIGI; ARTHUR, IAN; NORMAND, ANNE-CECILE; GIRALDO, ALEJANDRA; et al. International Society of Human and Animal Mycology (ISHAM)-ITS reference DNA barcoding database-the quality controlled standard tool for routine identification of human and animal pathogenic fungi. Medical Mycology, v. 53, n. 4, p. 313-337, MAY 2015. Web of Science Citations: 93. (07/08575-1)
ITURRIETA-GONZALEZ, ISABEL ANTONIETA; BARBOSA PADOVAN, ANA CAROLINA; BIZERRA, FERNANDO CESAR; HAHN, ROSANE CHRISTINE; COLOMBO, ARNALDO LOPES. Multiple Species of Trichosporon Produce Biofilms Highly Resistant to Triazoles and Amphotericin B. PLoS One, v. 9, n. 10, OCT 31 2014. Web of Science Citations: 26. (07/08575-1, 10/17179-5)
BIZERRA, FERNANDO CESAR; JIMENEZ-ORTIGOSA, CRISTINA; SOUZA, ANA CAROLINA R.; BREDA, GIOVANNI LUIS; QUEIROZ-TELLES, FLAVIO; PERLIN, DAVID S.; COLOMBO, ARNALDO L.. Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin. Antimicrobial Agents and Chemotherapy, v. 58, n. 4, p. 2438-2440, APR 2014. Web of Science Citations: 33. (12/04769-4, 07/08575-1, 12/04767-1, 10/17179-5)
JAFET OURIVES, ANA PAULA; GONCALVES, SARAH SANTOS; SIQUEIRA, RICARDO ANDREOTTI; REMONDI SOUZA, ANA CAROLINA; CANZIANI, MARIA EUGENIA F.; MANFREDI, SILVIA REGINA; CORREA, LUCI; COLOMBO, ARNALDO LOPES. High rate of Candida deep-seated infection in patients under chronic hemodialysis with extended central venous catheter use. REVISTA IBEROAMERICANA DE MICOLOGIA, v. 33, n. 2, p. 100-103, APR 30 2016. Web of Science Citations: 0. (12/04769-4, 12/04767-1)
SAMPAIO PINHATI, HENRIQUE MARCONI; CASULARI, LUIZ AUGUSTO; REMONDI SOUZA, ANA CAROLINA; SIQUEIRA, RICARDO ANDREOTTI; GOMES DAMASCENO, CAMILA MARIA; COLOMBO, ARNALDO LOPES. Outbreak of candidemia caused by fluconazole resistant Candida parapsilosis strains in an intensive care unit. BMC INFECTIOUS DISEASES, v. 16, AUG 20 2016. Web of Science Citations: 16. (12/04769-4, 12/04767-1)
MELO, ANALY S.; BIZERRA, FERNANDO C.; FREYMUELLER, EDNA; ARTHINGTON-SKAGGS, BETH A.; COLOMBO, ARNALDO L.. Biofilm production and evaluation of antifungal susceptibility amongst clinical Candida spp. isolates, including strains of the Candida parapsilosis complex. Medical Mycology, v. 49, n. 3, p. 253-262, APR 2011. Web of Science Citations: 78.
BIZERRA, FERNANDO C.; MELO, ANALY S. A.; KATCHBURIAN, EDUARDO; FREYMUELLER, EDNA; STRAUS, ANITA H.; TAKAHASHI, HELIO K.; COLOMBO, ARNALDO L.. Changes in Cell Wall Synthesis and Ultrastructure during Paradoxical Growth Effect of Caspofungin on Four Different Candida Species. Antimicrobial Agents and Chemotherapy, v. 55, n. 1, p. 302-310, JAN 2011. Web of Science Citations: 57. (07/04925-8)
MERSEGUEL, KARINA BELLINGHAUSEN; NISHIKAKU, ANGELA SATIE; RODRIGUES, ANDERSON MESSIAS; PADOVAN, ANA CAROLINA; CARMONA E FERREIRA, RENATA; DE AZEVEDO MELO, ANALY SALLES; DA SILVA BRIONES, MARCELO RIBEIRO; COLOMBO, ARNALDO LOPES. Genetic diversity of medically important and emerging Candida species causing invasive infection. BMC INFECTIOUS DISEASES, v. 15, FEB 13 2015. Web of Science Citations: 30. (07/08575-1)
FRANCO, JAQUES; FERREIRA, RENATA C.; IENNE, SUSAN; ZINGALES, BIANCA. ABCG-like transporter of Trypanosoma cruzi involved in benznidazole resistance: Gene polymorphisms disclose inter-strain intragenic recombination in hybrid isolates. INFECTION GENETICS AND EVOLUTION, v. 31, p. 198-208, APR 2015. Web of Science Citations: 11. (13/13333-8, 09/01230-4)
DE AZEVEDO BASTOS, VIVIANE REIS; DE CASTRO LIMA SANTOS, DANIEL WAGNER; BARBOSA PADOVAN, ANA CAROLINA; AZEVEDO MELO, ANALY SALLES; MAZZOLIN, MILENE DE ABREU; ARANHA CAMARGO, LUIS FERNANDO; COLOMBO, ARNALDO LOPES. Early Invasive Pulmonary Aspergillosis in a Kidney Transplant Recipient Caused by Aspergillus lentulus: First Brazilian Report. Mycopathologia, v. 179, n. 3-4, p. 299-305, APR 2015. Web of Science Citations: 8. (09/10155-6, 07/08575-1)
NEGRI, C. E.; GONCALVES, S. S.; XAFRANSKI, H.; BERGAMASCO, M. D.; AQUINO, V. R.; CASTRO, P. T. O.; COLOMBO, A. L.. Cryptic and Rare Aspergillus Species in Brazil: Prevalence in Clinical Samples and In Vitro Susceptibility to Triazoles. Journal of Clinical Microbiology, v. 52, n. 10, p. 3633-3640, OCT 2014. Web of Science Citations: 28. (12/01548-7, 12/01134-8, 12/19103-1)
NUNES, JORGE MENESES; BIZERRA, FERNANDO CESAR; CARMONA E FERREIRA, RENATA; COLOMBO, ARNALDO LOPES. Molecular Identification, Antifungal Susceptibility Profile, and Biofilm Formation of Clinical and Environmental Rhodotorula Species Isolates. Antimicrobial Agents and Chemotherapy, v. 57, n. 1, p. 382-389, JAN 2013. Web of Science Citations: 34. (07/08575-1, 09/01230-4, 10/17179-5)
GONCALVES, S. S.; AMORIM, C. S.; NUCCI, M.; PADOVAN, A. C. B.; BRIONES, M. R. S.; MELO, A. S. A.; COLOMBO, A. L.. Prevalence rates and antifungal susceptibility profiles of the Candida parapsilosis species complex: results from a nationwide surveillance of candidaemia in Brazil. Clinical Microbiology and Infection, v. 16, n. 7, p. 885-887, JUL 2010. Web of Science Citations: 45.
CHAGAS-NETO, THOMAS C.; CHAVES, GUILHERME M.; MELO, ANALY S. A.; COLOMBO, ARNALDO L.. Bloodstream Infections Due to Trichosporon spp.: Species Distribution, Trichosporon asahii Genotypes Determined on the Basis of Ribosomal DNA Intergenic Spacer 1 Sequencing, and Antifungal Susceptibility Testing. Journal of Clinical Microbiology, v. 47, n. 4, p. 1074-1081, APR 2009. Web of Science Citations: 77. (05/02006-0)
SOUZA, ANA CAROLINA R.; FERREIRA, RENATA C.; GONCALVES, SARAH S.; QUINDOS, GUILLERMO; ERASO, ELENA; BIZERRA, FERNANDO C.; BRIONES, MARCELO R. S.; COLOMBO, ARNALDO L.. Accurate Identification of Candida parapsilosis (Sensu Lato) by Use of Mitochondrial DNA and Real-Time PCR. Journal of Clinical Microbiology, v. 50, n. 7, p. 2310-2314, JUL 2012. Web of Science Citations: 19. (07/08575-1, 09/01230-4, 10/17179-5, 10/02752-1)
MAFRA, FERNANDO F. P.; GATTAI, PEDRO P.; MACEDO, MICHEL M.; MORI, MARCELO A.; ARAUJO, RONALDO C.. The angiotensin-I-converting enzyme insertion/deletion in polymorphic element codes for an AluYa5 RNA that downregulates gene expression. PHARMACOGENOMICS JOURNAL, v. 18, n. 4, p. 517-527, JUL 2018. Web of Science Citations: 0. (15/20082-7)
REMONDI SOUZA, ANA CAROLINA; FUCHS, BETH BURGWYN; ALVES, VIVIANE DE SOUZA; JAYAMANI, ELAMPARITHI; COLOMBO, ARNALDO LOPES; MYLONAKIS, ELEFTHERIOS. Pathogenesis of the Candida parapsilosis Complex in the Model Host Caenorhabditis elegans. GENES, v. 9, n. 8, AUG 2018. Web of Science Citations: 3. (12/04769-4, 17/02203-7, 13/07405-6)
MONFREDINI, PRISCILLA MORAIS; REMONDI SOUZA, ANA CAROLINA; CAVALHEIRO, RENAN PELLUZZI; SIQUEIRA, RICARDO ANDREOTTI; COLOMBO, ARNALDO LOPES. Clinical impact of Candida spp. biofilm production in a cohort of patients with candidemia. Medical Mycology, v. 56, n. 7, p. 803-808, OCT 2018. Web of Science Citations: 1. (12/04767-1)
ROSSATO, LUANA; COLOMBO, ARNALDO LOPES. Candida auris: What Have We Learned About Its Mechanisms of Pathogenicity?. FRONTIERS IN MICROBIOLOGY, v. 9, DEC 12 2018. Web of Science Citations: 0. (17/02203-7, 17/19095-2)
CHAGAS-NETO‚ T.C.; CHAVES‚ G.M.; COLOMBO‚ A.L.. Update on the genus Trichosporon. Mycopathologia, v. 166, n. 3, p. 121-132, 2008. (05/02006-0)
ROSENBERG, ALEXANDER; ENE, V, IULIANA; BIBI, MAAYAN; ZAKIN, SHIRI; SEGAL, ELLA SHTIFMAN; ZIV, NAOMI; DAHAN, ALON M.; COLOMBO, ARNALDO LOPES; BENNETT, RICHARD J.; BERMAN, JUDITH. Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia. NATURE COMMUNICATIONS, v. 9, JUN 25 2018. Web of Science Citations: 7. (17/02203-7)