Ludimila Dias Almeida in research grants and scholarships supported by FAPESP.
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Drugs need to reach their targets (present on the surface or inside the cells) in order to function. Traditionally the pharmaceutical industry has designed new compounds assuming that they would enter the cell by passive diffusion through the plasma membrane, however, there is a growing body of evidence indicating that passive diffusion entry is the exception rather than the rule. Studies…
The Agaricomycetes presents two morphological phases in their mushroom life-cycle, a transient monokaryotic and a dikaryotic, more durable. The events needed for the dikaryotization phenomenon are governed by mating type loci, organized in a tetrapolar system, formed by the multigenic A and B locus. The A locus codes for two homeodomains proteins named HD1 and HD2, while B locus presents …
Stage specific transition between the monokaryotic and dikaryotic phases of the mushroom life-cycle is governed by the genetics of the mating-type system. In these fungi, the mating-type loci are organized into a tetrapolar genetic structure that ensures that only fungi that differ in the two mating-type locus A and B can successfully undergo sexual diazotization (mating). The evolution o…
The drug development for diseases that affect the Central Nervous System (CNS) should consider the transport of the compound through the human Blood Brain Barrier (BBB). Due to the protective function of this barrier, the entrance of xenobiotic molecules is restricted and occurs preferentially via membrane carriers present in the BBB cells. Hence, the development of methodologies for the …
| 4 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 4 | All Scholarships |
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