Abstract
Desmoid tumors are mesenchymal fibroblastic proliferations that despite the absolute lack of ability to metastasize are extremely locally invasive. Previous studies reported that sporadic desmoids are usually associated with somatic mutations in b-catenin (CTNNB1) and that desmoid tumors occurring in the background of familial adenomatous polyposis (FAP) usually contain inactivating germl…