Roberto Passetto Falcão
CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Medicina Ribeirão Preto from Universidade de São Paulo (1966) and ph.d. at Clinica Médica Ribeirão Preto from Universidade de São Paulo (1972). Has experience in Medicine, focusing on Clinical Medicine, acting on the following subjects: leucemia promielocitica, anemia aplastica, leucemia linfoide aguda, leucemia mielóide aguda and linfocitos. (Source: Lattes Curriculum)
- INCT 2014: in Stem Cell and Cell Therapy, AP.TEM
Abstract
The present proposal establishes the continuity and expansion of the activities of the National Institute of Science and Technology in Stem Cells and Cell Therapy, one of the National Institutes of Science and Technology created by CNPq/FAPESP in 2008. In that opportunity, we proposed the development of an extensive program of basic and clinical research to understand, isolate, culture ...
- CTC - Center for Cell-Based Therapy, AP.CEPID
Abstract
We propose a program of basic and clinical research to isolate, culture, and characterize embryonic ,somatic, and neoplastic stem cells in order to understand their biology and apply this knowledge to therapy, comprising four research lines: (1) pluripotent stem cells (SC) (embryonic SC and induced pluripotent SC); (2) somatic SC (hematopoietic SC, mesenchymal SC, endothelial SC, and ca...
- Studies of genetic and epigenetic mechanisms in telomere associated genes: their clinical importance in lymphoid malignancies, AP.R
Abstract
Telomeres are ribonucleopreoteins at the linear chromosome ends and they serve as a protection against degradation and fusions, thus preserving the genomic information. When telomeres become critically short, due to either cell division or telomerase complex deficiency, telomeres are dysfunctional and induce cell senescence and apoptosis, but also lead to genomic instability. Telomere s...
- National Institute of Science and Technology in Cell Therapy, AP.TEM
Abstract
Cell therapy is the use of cells for therapeutically objectives. These cells can be used systemically or locally in affected tissues or organs. The cells also vary with regard to the state of maturation and differentiation. Examples of successful stem cell (SC) therapies have appeared in recent years and the search for new therapies has brought new hope for the treatment of some illness...
- Center for Research on Cell-Based Therapy, AP.CEPID
Abstract
Description of the Center and its characteristic features. The Center is composed of researchers in the fields of human cytology, molecular and population, genetics, immunology, protein chemistry, cell culture, blood coagulation, transplantation biology, transfusion medicine and hematology, who have collaborated in different associations in the past and work in three closely located fac...
| 2 / 2 | Ongoing research grants |
| 6 / 3 | Completed research grants |
| 4 / 0 | Completed scholarships in Brazil |
| 12 / 5 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 19 |
| Citations | 156 |
| Cit./Article | 8.2 |
| Data from Web of Science | |
BRESSAN, FABIANA FERNANDES; FANTINATO-NETO, PAULO; ANDRADE, GABRIELLA MAMEDE; SANGALLI, JULIANO RODRIGUES; SAMPAIO, RAFAEL VILAR; DA SILVEIRA, JULIANO COELHO; PERECIN, FELIPE; MEIRELLES, FLAVIO VIEIRA. Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles. Ciência Rural, v. 45, n. 10, p. 1879-1886, OCT 2015. Web of Science Citations: 1. (08/57877-3, 14/21034-3, 13/08135-2)
BRESSAN, FABIANA F.; SANGALLI, JULIANO R.; PESSA, LAIS V. F.; PIRES, PEDRO R. L.; MEIRELLES, FLAVIO V.. Insights on bovine genetic engineering and cloning. Pesquisa Veterinária Brasileira, v. 33, n. 1, p. 113-118, DEC 2013. Web of Science Citations: 1. (08/57877-3, 09/11631-6, 11/08376-4, 08/00102-0)
FONTES, A. M.; MELO, F. U. F.; GREENE, L. J.; FACA, V. M.; LIN, Y.; GERSON, S. L.; COVAS, D. T.. Production of human factor VIII-FL in 293T cells using the bicistronic MGMT(P140K)-retroviral vector. Genetics and Molecular Research, v. 11, n. 1, p. 775-789, 2012. Web of Science Citations: 2. (98/14247-6, 08/57877-3)
DE OLIVEIRA, FABIO MORATO; PALMA, LEONARDO DE CARVALHO; FALCAO, ROBERTO PASSETTO; SIMOES, BELINDA PINTO. A new dic(7;12)(p12.21;p12.2) and i(12)(q10) during the lymphoid blast crisis of patient with Ph plus chronic myeloid leukemia. MEDICAL ONCOLOGY, v. 29, n. 4, p. 2332-2336, DEC 2012. Web of Science Citations: 1.
DALMAZZO, LEANDRO F. F.; JACOMO, RAFAEL H.; MARINATO, ANDRE F.; FIGUEIREDO-PONTES, LORENA L.; CUNHA, RENATO L. G.; GARCIA, AGLAIR B.; REGO, EDUARDO M.; FALCAO, ROBERTO P.. The presence of CD56/CD16 in T-cell acute lymphoblastic leukaemia correlates with the expression of cytotoxic molecules and is associated with worse response to treatment. British Journal of Haematology, v. 144, n. 2, p. 223-229, JAN 2009. Web of Science Citations: 18. (05/04296-5)
DE OLIVEIRA, FABIO MORATO; LUCENA-ARAUJO, ANTONIO ROBERTO; FAVARIN, MARIA DO CARMO; BONINI PALMA, PATRICIA VIANNA; REGO, EDUARDO MAGALHAES; FALCAO, ROBERTO PASSETTO; COVAS, DIMAS TADEU; FONTES, APARECIDA MARIA. Differential expression of AURKA and AURKB genes in bone marrow stromal mesenchymal cells of myelodysplastic syndrome: correlation with G-banding analysis and FISH. Experimental Hematology, v. 41, n. 2, p. 198-208, FEB 2013. Web of Science Citations: 16. (11/01647-2)
UEDA YAOCHITE, JULIANA NAVARRO; CALIARI-OLIVEIRA, CAROLINA; BOTELHO DE SOUZA, LUCAS EDUARDO; NETO, LOURENCO SBRAGIA; BONINI PALMA, PATRICIA VIANNA; COVAS, DIMAS TADEU; RIBEIRO MALMEGRIM, KELEN CRISTINA; VOLTARELLI, JULIO CESAR; DONADI, EDUARDO ANTONIO. Therapeutic efficacy and biodistribution of allogeneic mesenchymal stem cells delivered by intrasplenic and intrapancreatic routes in streptozotocin-induced diabetic mice. STEM CELL RESEARCH & THERAPY, v. 6, MAR 14 2015. Web of Science Citations: 16. (10/11759-0, 08/57877-3)
DE OLIVEIRA, G. L. V.; FERREIRA, A. F.; GASPAROTTO, E. P. L.; KASHIMA, S.; COVAS, D. T.; GUERREIRO, C. T.; BRUM, D. G.; BARREIRA, A. A.; VOLTARELLI, J. C.; SIMOES, B. P.; et al. Defective expression of apoptosis-related molecules in multiple sclerosis patients is normalized early after autologous haematopoietic stem cell transplantation. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, v. 187, n. 3, p. 383-398, MAR 2017. Web of Science Citations: 4. (08/57877-3)
CASTILHO-FERNANDES, ANDRIELLE; FONTES, APARECIDA MARIA; ABRAHAM, KURUVILLA JOSEPH; CORREA DE FREITAS, MARCELA CRISTINA; DA ROSA, NATHALIA GONSALES; PICANCO-CASTRO, VIRGINIA; DE SOUSA RUSSO-CARBOLANTE, ELISA MARIA; COVAS, DIMAS TADEU. Significant differences in integration sites of Moloney murine leukemia virus/Moloney murine sarcoma virus retroviral vector carrying recombinant coagulation factor IX in two human cell lines. Biotechnology Letters, v. 37, n. 5, p. 991-1001, MAY 2015. Web of Science Citations: 0. (98/14247-6, 08/57877-3)
DE ARAUJO, LUIZA F.; FONSECA, ALINE S.; MUYS, BRUNA R.; PLACA, JESSICA R.; BUENO, RAFAELA B. L.; LORENZI, JULIO C. C.; SANTOS, ANEMARI R. D.; MOLFETTA, GREICE A.; ZANETTE, DALILA L.; SOUZA, JORGE E. S.; et al. Mitochondrial genome instability in colorectal adenoma and adenocarcinoma. TUMOR BIOLOGY, v. 36, n. 11, p. 8869-8879, NOV 2015. Web of Science Citations: 10. (08/57877-3, 13/08135-2)
C.G. MACHADO; R.T. CALADO; A.B. GARCIA; R.P. FALCÃO. Age-related changes of the multidrug resistance P-glycoprotein function in normal human peripheral blood T lymphocytes. Brazilian Journal of Medical and Biological Research, v. 36, n. 12, p. 1653-1657, Dez. 2003. (98/14247-6)
UEDA YAOCHITE, JULIANA NAVARRO; ALVES DE LIMA, KALIL WILLIAN; CALIARI-OLIVEIRA, CAROLINA; BONINI PALMA, PATRICIA VIANNA; BARRA COURI, CARLOS EDUARDO; SIMOES, BELINDA PINTO; COVAS, DIMAS TADEU; VOLTARELLI, JULIO CESAR; OLIVEIRA, MARIA CAROLINA; DONADI, EDUARDO ANTONIO; et al. Multipotent mesenchymal stromal cells from patients with newly diagnosed type 1 diabetes mellitus exhibit preserved in vitro and in vivo immunomodulatory properties. STEM CELL RESEARCH & THERAPY, v. 7, JAN 18 2016. Web of Science Citations: 19. (10/11759-0, 08/57877-3)
ARRUDA, LUCAS C. M.; DE AZEVEDO, JULIA T. C.; DE OLIVEIRA, GISLANE L. V.; SCORTEGAGNA, GABRIELA T.; RODRIGUES, EVANDRA S.; PALMA, PATRICIA V. B.; BRUM, DORALINA G.; GUERREIRO, CARLOS T.; MARQUES, VANESSA D.; BARREIRA, AMILTON A.; et al. Immunological correlates of favorable long-term clinical outcome in multiple sclerosis patients after autologous hematopoietic stem cell transplantation. Clinical Immunology, v. 169, p. 47-57, AUG 2016. Web of Science Citations: 15. (08/57877-3, 13/08135-2)
DE OLIVEIRA, FABIO MORATO; DE FIGUEIREDO PONTES, LORENA LOBO; BASSI, SARAH CRISTINA; FIGUEIREDO DALMAZZO, LEANDRO FELIPE; FALCAO, ROBERTO PASSETTO. Co-existence of t(6;13)(p21;q14.1) and trisomy 12 in chronic lymphocytic leukemia. MEDICAL ONCOLOGY, v. 29, n. 2, p. 1227-1230, JUN 2012. Web of Science Citations: 0.
DALMAZZO, LEANDRO F. F.; SANTANA-LEMOS, BARBARA A.; JACOMO, RAFAEL H.; GARCIA, AGLAIR B.; REGO, EDUARDO M.; DA FONSECA, LUIZ M.; FALCAO, ROBERTO P.. Antibody-targeted horseradish peroxidase associated with indole-3-acetic acid induces apoptosis in vitro in hematological malignancies. Leukemia Research, v. 35, n. 5, p. 657-662, MAY 2011. Web of Science Citations: 12. (98/14247-6, 05/04296-5)
LUCENA-ARAUJO, ANTONIO R.; DE OLIVEIRA, FABIO MORATO; LEITE-CUEVA, SABRINA DIAS; DOS SANTOS, GUILHERME AUGUSTO; FALCAO, ROBERTO PASSETO; REGO, EDUARDO MAGALHAES. High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia. Leukemia Research, v. 35, n. 2, p. 260-264, FEB 2011. Web of Science Citations: 36.
DE OLIVEIRA, FABIO MORATO; BRANDAO, RENATA AMORIM; LEITE-CUEVA, SABRINA DIAS; CARETA, FRANCISCO DE PAULA; SIMOES, BELINDA PINTO; REGO, EDUARDO MAGALHAES; FALCAO, ROBERTO PASSETTO. Tetrasomy 8 in a patient with chronic lymphocytic leukemia. Cancer Genetics and Cytogenetics, v. 198, n. 2, p. 166-169, APR 15 2010. Web of Science Citations: 2.
DE OLIVEIRA, FABIO MORATO; LUCENA-ARAUJO, ANTONIO ROBERTO; LEITE-CUEVA, SABRINA D.; SANTOS, GUILHERME AUGUSTO S.; REGO, EDUARDO M.; FALCAO, ROBERTO P.. Segmental amplification of MLL gene associated with high expression of AURKA and AURKB genes in a case of acute monoblastic leukemia with complex karyotype. Cancer Genetics and Cytogenetics, v. 198, n. 1, p. 62-65, APR 1 2010. Web of Science Citations: 2.
DAVANSO, MARIANA RODRIGUES; CALIARI-OLIVEIRA, CAROLINA; BARRA COURI, CARLOS EDUARDO; COVAS, DIMAS TADEU; DE OLIVEIRA LEAL, ANGELA MERICE; VOLTARELLI, JULIO CESAR; RIBEIRO MALMEGRIM, KELEN CRISTINA; UEDA YAOCHITE, JULIANA NAVARRO. DPP-4 Inhibition Leads to Decreased Pancreatic Inflammatory Profile and Increased Frequency of Regulatory T Cells in Experimental Type 1 Diabetes. Inflammation, v. 42, n. 2, p. 449-462, APR 2019. Web of Science Citations: 0. (08/57877-3, 10/02074-3)
DANIEL MAZZA MATOS; ROBERTO PASSETTO FALCÃO. Monoclonal B-cell lymphocytosis: a brief review for general clinicians. São Paulo Medical Journal, v. 129, n. 3, p. -, Maio 2011.
CALADO‚ RT; MACHADO‚ CG; CARNEIRO‚ JJ; GARCIA‚ AB; FALCÃO‚ RP. Age-related changes of P-glycoprotein-mediated rhodamine 123 efflux in normal human bone marrow hematopoietic stem cells. LEUKEMIA, v. 17, n. 4, p. 816-818, 2003. (98/14247-6)
DE FIGUEIREDO PESSOA, LAIS VICARI; LISBOA PIRES, PEDRO RATTO; DEL COLLADO, MAITE; GODOY PIERI, NAIRA CAROLINE; RECCHIA, KAIANA; SOUZA, ALINE FERNANDA; PERECIN, FELIPE; DA SILVEIRA, JULIANO COELHO; CESAR DE ANDRADE, ANDRE FURUGEN; AMBROSIO, CARLOS EDUARDO; et al. Generation and miRNA Characterization of Equine Induced Pluripotent Stem Cells Derived from Fetal and Adult Multipotent Tissues. STEM CELLS INTERNATIONAL, 2019. Web of Science Citations: 1. (12/50533-2, 13/17955-3, 08/57877-3, 15/26818-5, 14/22887-0, 13/08135-2)