Israel Tojal da Silva
CV Lattes
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Fundação Antonio Prudente (FAP). A C Camargo Cancer Center (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Ciência da Computação from Universidade Paulista (2001). Has experience in Computer Science, focusing on Core Software, acting on the following subjects: bioinformatics, bioinformática, polybayes, single nucleotide polymorphism (snp) and gene expression. (Source: Lattes Curriculum)
- INCT 2014: on Oncogenomics and Therapeutic Inovations, AP.TEM
Abstract
INCiTO-INOTE will continue to support the scientific program previously created by the INCiTO, exploring bench-to-bedside-to-bench concepts, in order to face the challenges that are still limiting cancer prevention, diagnosis and treatment. The Institute will explore its large experience in genetics, epigenetics “comics”, bioinformatics and biomarkers to focus in areas where it can be w...
- Retrotransposons and nucleic acid-editing enzymes: activation, somatic events and association with cancer, AP.R
Abstract
Retrotransposable or Mobile Elements (MEs) comprise a constant threat to host genome due to their spontaneous mutational capabilities in DNA. To ensure such a level of propagation, a family of nucleic acid-modifying enzymes acts to mobilize the deleterious effects of the MEs. However, what could be regarded as a mechanism of protection to the integrity of the genome may be a source of c...
- Impact of the race factor on progression and biology of melanoma and non-small cell lung carcinoma, BP.MS
Abstract
Race refers to a population with common genetic and phenotypic features that separate them from other populations. Population studies suggest biological differences between races, in multiple aspects, such as: mutations, obesity, chronic inflammation and immune system, being, therefore, a relevant factor to be considered in the emergence and progression of diseases. Melanoma and non-sma...
- Fungal microbiome in human tumours, BP.DR
Abstract
The human microbiome is the group established between the interactions of body sites and the microbes communities that reside within. With the advances in molecular technologies, the existence of a great microorganisms diversity that wasn't detected before was revealed. Thus, new evidence of the role of microorganisms in host health was emerging. The study of the interaction between mic...
- Investigation of mutational signatures in Gastric Adenocarcinomas and evaluation of its possible prognostic impacts, BP.MS
Abstract
Gastric Adenocarcinomas (GAs) are highly aggressive neoplasms with a high incidence in Brazil. The highest world rates of GA's mortality are due to few clinical signs of the disease in its early stages, which leads to late detection in most cases. Because of strong genetic and environmental component in GA etiology, the search for the causing somatic mutations processes that contribut...
| 1 / 1 | Ongoing research grants |
| 1 / 1 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 2 / 1 | Completed scholarships in Brazil |
| 6 / 5 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ROSALES, RAFAEL A.; DRUMMOND, RODRIGO D.; VALIERIS, RENAN; DIAS-NETO, EMMANUEL; DA SILVA, ISRAEL T.. signeR: an empirical Bayesian approach to mutational signature discovery. Bioinformatics, v. 33, n. 1, p. 8-16, JAN 1 2017. Web of Science Citations: 16. (15/19324-6, 14/26897-0)