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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Apatite bone cement reinforced with calcium silicate fibers

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Motisuke, Mariana [1] ; Santos, Veronica R. [1] ; Bazanini, Naiana C. [1] ; Bertran, Celso A. [2]
Total Authors: 4
[1] UNIFESP, Inst Sci & Technol, Bioceram Lab, Sao Jose Dos Campos, SP - Brazil
[2] Univ Estadual Campinas, Inst Chem, Dept Phys Chem, Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE; v. 25, n. 10, p. 2357-2363, OCT 2014.
Web of Science Citations: 11

Several research efforts have been made in the attempt to reinforce calcium phosphate cements (CPCs) with polymeric and carbon fibers. Due to their low compatibility with the cement matrix, results were not satisfactory. In this context, calcium silicate fibers (CaSiO3) may be an alternative material to overcome the main drawback of reinforced CPCs since, despite of their good mechanical properties, they may interact chemically with the CPC matrix. In this work CaSiO3 fibers, with aspect ratio of 9.6, were synthesized by a reactive molten salt synthesis and used as reinforcement in apatite cement. 5 wt.% of reinforcement addition has increased the compressive strength of the CPC by 250 % (from 14.5 to 50.4 MPa) without preventing the cement to set. Ca and Si release in samples containing fibers could be explained by CaSiO3 partial hydrolysis which leads to a quick increase in Ca concentration and in silica gel precipitation. The latter may be responsible for apatite precipitation in needle like form during cement setting reaction. The material developed presents potential properties to be employed in bone repair treatment. (AU)

FAPESP's process: 11/09240-9 - Calcium phosphate cement otimization for application in orthopedics and tissue engineering
Grantee:Mariana Motisuke
Support type: Regular Research Grants
FAPESP's process: 12/07556-1 - Calcium phosphate cements containing CaSiO3 whiskers and gelatin: enhancement of mechanical strength and porosity control
Grantee:Verônica Ribeiro dos Santos
Support type: Scholarships in Brazil - Scientific Initiation