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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cell Adhesion to Plasma-Coated PVC

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Rangel, Elidiane C. [1] ; de Souza, Eduardo S. [1] ; de Moraes, Francine S. [1] ; Duek, Eliana A. R. [2] ; Lucchesi, Carolina [2] ; Schreiner, Wido H. [3] ; Durrant, Steven F. [1] ; Cruz, Nilson C. [1]
Total Authors: 8
[1] Univ Estadual Paulista UNESP, Lab Plasmas Tecnol, BR-18087180 Sorocaba, SP - Brazil
[2] Pontificia Univ Catolica, Dept Ciencias Fisiol, Lab Biomat, BR-18030095 Sorocaba, SP - Brazil
[3] Univ Fed Parana, Dept Fis, Lab Superficies & Interfaces, BR-81531990 Curitiba, Parana - Brazil
Total Affiliations: 3
Document type: Journal article
Web of Science Citations: 1

To produce environments suitable for cell culture, thin polymer films were deposited onto commercial PVC plates from radiofrequency acetylene-argon plasmas. The proportion of argon in the plasmas, P-Ar, was varied from 5.3 to 65.8%. The adhesion and growth of Vero cells on the coated surfaces were examined for different incubation times. Cytotoxicity tests were performed using spectroscopic methods. Carbon, O, and N were detected in all the samples using XPS. Roughness remained almost unchanged in the samples prepared with 5.3 and 28.9% but tended to increase for the films deposited with P-Ar between 28.9 and 55.3%. Surface free energy increased with increasing P-Ar, except for the sample prepared at 28.9% of Ar, which presented the least reactive surface. Cells proliferated on all the samples, including the bare PVC. Independently of the deposition condition there was no evidence of cytotoxicity, indicating the viability of such coatings for designing biocompatible devices. (AU)

FAPESP's process: 05/03420-4 - Protective coatings prepared by plasma processes
Grantee:Elidiane Cipriano Rangel da Cruz
Support type: Regular Research Grants
FAPESP's process: 11/21345-0 - Thin hydrogenated amorphous carbon films also containing Halogens produced by Plasma Enhanced Chemical Vapor Deposition (PECVD) and plasma immersion ion implantation and deposition (PIIID)
Grantee:Steven Frederick Durrant
Support type: Regular Research Grants