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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Systemic antibiotics in the treatment of periodontitis

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Author(s):
Feres, Magda ; Figueiredo, Luciene C. ; Soares, Geisla M. Silva ; Faveri, Marcelo
Total Authors: 4
Document type: Review article
Source: PERIODONTOLOGY 2000; v. 67, n. 1, p. 131-186, FEB 2015.
Web of Science Citations: 50
Abstract

Despite the fact that several clinical studies have shown additional benefits when certain systemic antibiotics are used as adjuncts to periodontal treatment, clear guidelines for the use of these agents in the clinical practice are not yet available. Basic questions concerning the use of systemic antibiotics to treat periodontitis remain unanswered, such as: which drug(s) should be used; which patients would most benefit from treatment; which are the most effective protocols (i.e. doses and durations); and in which phase of the mechanical therapy should the drug(s) be administered? Although not all of those questions have been directly addressed by controlled randomized clinical trials, recent concepts related to the ecology of periodontal diseases, as well as the major advances in laboratory and clinical research methods that have occurred in the past decade, have significantly broadened our knowledge in this field. This article endeavored to provide a state of the art' overview on the use of systemic antibiotics in the treatment of periodontitis, based on the most recent literature on the topic as well as on a compilation of data from studies conducted at the Center of Clinical Trials at Guarulhos University (SAo Paulo, Brazil) from 2002 to 2012. (AU)

FAPESP's process: 10/10384-2 - Effect of full-mouth disinfection compared with conventional scaling and root planning with chlorhexidine.
Grantee:Luciene Cristina de Figueiredo
Support Opportunities: Regular Research Grants
FAPESP's process: 11/23034-2 - Clinical and microbiological outcomes of timing of administration of systemic amoxicillin plus metronidazole associated with SRP in the treatment of subjcts with periodontitis
Grantee:Marcelo de Faveri
Support Opportunities: Regular Research Grants
FAPESP's process: 09/17677-8 - Clinical and microbiological influence of the dose and duration of systemic antibiotics in the treatment of chronic periodontitis.
Grantee:Magda Feres Figueiredo
Support Opportunities: Regular Research Grants
FAPESP's process: 07/56413-0 - Clinical and microbiological effects of amoxicillin and metronidazole systemic association to scaling and root planing in subjects with generalized aggressive periodontitis
Grantee:Marcelo de Faveri
Support Opportunities: Regular Research Grants