| Full text | |
| Author(s): |
Miura, Barbara A.
[1]
;
Ferreira, Natalia H.
[1]
;
Oliveira, Pollyanna F.
[1]
;
de Faria, Emerson H.
[1]
;
Tavares, Denise C.
[1]
;
Rocha, Lucas A.
[1]
;
Ciuffi, Katia J.
[1]
;
Nassar, Eduardo J.
[1]
Total Authors: 8
|
| Affiliation: | [1] Univ Franca, BR-14404600 Franca, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | Journal of Luminescence; v. 159, p. 93-99, MAR 2015. |
| Web of Science Citations: | 12 |
| Abstract | |
Over the last decades, researchers have explored nanotechnological applications in different areas. The non-hydrolytic and hydrolytic sol-gel routes offer the ideal conditions to obtain materials with distinct compositions and multifunctionality, for use in such diverse areas as nanomedicine and technology. In this work, we used the modified hydrolytic sol-gel route to prepare YVO4 doped with Eu3+ ion. The YVO4:Eu3+ nanoparticles were functionalized with 3-chloropropyltriethoxysilane using the hydrolytic sol-gel process; the drug cisplatin was then added to them. The final powder was characterized by thermal analysis, infrared spectroscopy, X-ray diffraction, and photoluminescence. The powder X-ray diffraction patterns of the samples obtained before and after functionalization revealed well defined peaks ascribed to the tetragonal structure of the YVO4 phase. The thermal analysis curves evidenced mass loss relative to 3-chloropropyltriethoxysilane and cisplatin decomposition. Infrared spectroscopy showed the peaks related to the CH and NH groups vibration modes, confirming YVO4 functionalization. The excitation and emission spectrum of the Eu3+ ion did not change upon its doping into the matrix functionalized with 3-chloropropyl and cisplatin. Cytotoxicity tests conducted on normal Chinese hamster (V79 cells) and murine melanoma (B16F10) cells attested that the matrix was not toxic. (C) 2014 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 12/24427-0 - Evaluation of antitumoral activity and toxicological parameters of cisplatin functionalized nanoparticles of yttrium vanadate |
| Grantee: | Natália Helen Ferreira |
| Support Opportunities: | Scholarships in Brazil - Master |
| FAPESP's process: | 11/21310-2 - Study of cytotoxic, genotoxic and antioxidant activities of Styrax camporum hydroalcoholic extract and chemical markers, egonol and homoegonol, and their influence on genetic material damage and pre-neoplastic lesions. |
| Grantee: | Pollyanna Francielli de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 12/11673-3 - Thin films obtained by spin and dip-coating using sol-gel methodology |
| Grantee: | Eduardo José Nassar |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/09823-4 - Use of the europium III to reveal structure of the matrices obtained by sol-gel methodology |
| Grantee: | Eduardo José Nassar |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 11/15757-4 - Synthesis and characterization of LaNbO4:Eu3+, Bi3+ doped matrix obtained by spray pyrolysis process |
| Grantee: | Lucas Alonso Rocha |
| Support Opportunities: | Regular Research Grants |