| Full text | |
| Author(s): |
Amaral, Monica F. Z. J.
[1]
;
Baumgartner, Amanda A.
[1]
;
Vessecchi, Ricardo
[2]
;
Clososki, Giuliano C.
[1]
Total Authors: 4
|
| Affiliation: | [1] Univ Sao Paulo, Nucleo Pesquisas Prod Nat & Sintet, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Dept Quim, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | ORGANIC LETTERS; v. 17, n. 2, p. 238-241, JAN 16 2015. |
| Web of Science Citations: | 22 |
| Abstract | |
A variety of C-2 and C-5 difunctionalized indolizines have been prepared through the reaction of 1-ester-substituted indolizines with organometallic bases followed by a reaction with different electrophiles. Metalation takes place under mild conditions allowing the isolation of a number of difunctionalized indolizines in good yields. The regioselectivity of the reaction appears to be governed by the nature of the base and electrophile. (AU) | |
| FAPESP's process: | 13/04766-8 - Applycation of new organometallic reagents in the functionalization of substances of synthetic interest |
| Grantee: | Giuliano Cesar Clososki |
| Support type: | Regular Research Grants |
| FAPESP's process: | 11/20742-6 - Application of organometallic reagents in the functionalization of indolizines of synthetic interest |
| Grantee: | Mônica Franco Zannini Junqueira Toledo |
| Support type: | Scholarships in Brazil - Doctorate |