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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Trueperella pyogenes multispecies infections in domestic animals: a retrospective study of 144 cases (2002 to 2012)

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Author(s):
Ribeiro, M. G. [1] ; Risseti, R. M. [1] ; Bolanos, C. A. D. [2] ; Caffaro, K. A. [2] ; de Morais, A. C. B. [2] ; Lara, G. H. B. [1] ; Zamprogna, T. O. [1] ; Paes, A. C. [1] ; Listoni, F. J. P. [1] ; Franco, M. M. J. [2]
Total Authors: 10
Affiliation:
[1] Sao Paulo State Univ, UNESP, Dept Vet Hyg & Publ Hlth, Botucatu, SP - Brazil
[2] Sch Vet, San Juan De Pasto - Colombia
Total Affiliations: 2
Document type: Journal article
Source: VETERINARY QUARTERLY; v. 35, n. 2, p. 82-87, APR 3 2015.
Web of Science Citations: 30
Abstract

Background: Formerly, Arcanobacterium pyogenes was recently renamed Trueperella pyogenes. This opportunistic bacterium is related to miscellaneous pyogenic infections in animals. Most studies involving T. pyogenes are case reports, whereas few surveys have focused the major aspects of T. pyogenes infections involving a case series study design. Objective: The aim of this study was to retrospectively evaluate selected epidemiological and clinical aspects, as well as the in vitro antimicrobial susceptibility pattern of 144 cases of T. pyogenes infections among domestic animals from 2002 to 2012. Animals and methods: T. pyogenes was isolated from different clinical specimens from cattle, goats, sheep, pigs, horses, dogs, and buffaloes. Correlations were assessed by the Chi-square or Fisher's exact tests. Results: Mastitis (45.1%), abscesses (18.0%), pneumonia (11.1%), and lymphadenitis (9.0%) were the most common clinical manifestations. In addition, the organism was also isolated from other miscellaneous clinical specimens from cases of septicemia, encephalitis, pyometra, prostatitis, orchitis, seminal vesiculitis, pericarditis, and omphalitis. No statistical association was observed between T. pyogenes infections and age, gender, or season across the study. The most effective drugs against the pathogen were florfenicol (99.1%), cefoperazone (96.0%), cephalexin (95.0%), and ceftiofur (94.8%). High resistance rates were observed against trimethoprim-sulfamethoxazole (49.3%), followed by norfloxacin (10.9%) and tetracycline (9.2%). Conclusions: This study highlights the diversity of clinical manifestations and the opportunistic behavior of T. pyogenes infections in domestic animals, with predominance of mastitis, abscesses, pneumonia, and lymphadenitis. It also reinforces the importance of knowing the susceptibility profile before initiating therapy, to improve antimicrobial therapy approaches. (AU)

FAPESP's process: 13/17293-0 - Phenotypic characterization and virulence-associated genes in strains of Trueperella (Arcanobacterium) pyogenes isolated from bovine mastites
Grantee:Rafaela Mastrangelo Risseti
Support Opportunities: Scholarships in Brazil - Master