Is the chronotype associated with obstructive sleep apnea?

Author(s)

Kim, Lenise Jihe ^[1] ; Coelho, Fernando Morgadinho ^{[1, 2]} ; Hirotsu, Camila ^[1] ; Bittencourt, Lia ^[1] ; Tufik, Sergio ^[1] ; Andersen, Monica Levy ^[1]

Affiliation

^[1] Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo UNIFESP, Dept Neurol & Neurocirurgia, BR-04024002 Sao Paulo - Brazil

• Document type: Journal article
• Source: Sleep and Breathing; v. 19, n. 2, p. 645-651, MAY 2015.
• Web of Science Citations: 3

Abstract

Chronotype and obstructive sleep apnea (OSA) appear to have a similar lifelong evolution, which could indicate a possible effect of morningness or eveningness in the apnea-hypopnea index (AHI). The present study aimed to examine the prevalence of chronotypes in a representative sample of So Paulo city residents and to investigate the effect of chronotypes on the severity of OSA. We performed a cross-sectional analysis using the So Paulo Epidemiologic Sleep Study (EPISONO). All participants underwent a full-night polysomnography and completed the Morningness-eveningness, Epworth Sleepiness Scale, and UNIFESP Sleep questionnaires. Chronotypes were classified as morning-type, evening-type, and intermediate. Morning-type individuals represented 52.1 % of the sample, followed by intermediate (39.5 %), and evening-type (8.4 %) individuals. After stratifying the sample by body mass index (BMI) (> 26.8 kg/m(2)) and age (> 42 years), we observed increased AHI values in morning- and evening-type individuals. We demonstrated, for the first time, an age- and BMI-related effect of morning- and evening-types in OSA severity, suggesting that the intermediate chronotype might play a role as a protective factor in older and overweight patients. (AU)

• FAPESP's process: 13/14420-1 - The effects of sleep restriction in an animal model of ischemic brain injury
• Grantee: Lenise Jihe Kim
• Support Opportunities: Scholarships in Brazil - Master