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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Oral aspects in celiac disease children: clinical and dental enamel chemical evaluation

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Author(s):
de Carvalho, Fabricio Kitazono [1] ; de Queiroz, Alexandra Mussolino [1] ; Bezerra da Silva, Raquel Assed [1] ; Sawamura, Regina [2] ; Bachmann, Luciano [3] ; Bezerra da Silva, Lea Assed [1] ; Nelson-Filho, Paulo [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Pediat Dent, BR-14040904 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Childcare & Pediat, BR-14040904 Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Sch Philosophy Sci & Letters Ribeirao Preto, Dept Phys, BR-14040904 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY; v. 119, n. 6, p. 636-643, JUN 2015.
Web of Science Citations: 12
Abstract

Objective. The aim of this study was to evaluate the oral manifestations of celiac disease (CD), the chemical composition of dental enamel, and the occurrence of CD in children with dental enamel defects (DEDs). Study Design. In the study, 52 children with CD and 52 controls were examined for DEDs, recurrent aphthous stomatitis (RAS), dental caries experience, and salivary parameters. In addition, 10 exfoliated primary enamel molars from each group were analyzed by energy dispersive x-ray spectroscopy and Fourier transform infrared spectroscopy. Fifty children with DEDs were submitted to CD diagnosis. Results. Among the children with CD, a higher prevalence of DEDs (P = .00001) and RAS (P = .0052), lower caries experience (P = .0024), and reduction of salivary flow (P = .0060) were observed. Dental enamel from the children with CD demonstrated a lower calcium-to-phosphorus ratio (P = .0136), but no difference in the carbonate-to-phosphate ratio (P = .5862) was observed. In the multivariate analysis, CD was a protective factor for caries (OR = 0.74) and a risk factor for RAS (OR3.23). Conclusions. The children with CD presented with more RAS, DEDs, reduction of salivary flow, and chemical alterations in the enamel. (AU)

FAPESP's process: 10/20482-1 - Celiac disease: oral impact and study of enamel as a marker of disease, in children
Grantee:Alexandra Mussolino de Queiroz
Support type: Regular Research Grants