| Full text | |
| Author(s): |
de Araujo, Mariceli L.
[1]
;
Rodrigues, Anderson M.
[2]
;
Fernandes, Geisa F.
[2]
;
de Camargo, Zoilo P.
[2]
;
de Hoog, G. Sybren
[3]
Total Authors: 5
|
| Affiliation: | [1] Fed Univ Espirito Santo UFES, Dept Pathol, Vitoria - Brazil
[2] Fed Univ Sao Paulo UNIFESP, Dept Microbiol Immunol & Parasitol, Div Cell Biol, Sao Paulo - Brazil
[3] KNAW Fungal Biodivers Ctr, Cent Bur Schimmelcultures, Utrecht - Netherlands
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | MYCOSES; v. 58, n. 8, p. 485-490, AUG 2015. |
| Web of Science Citations: | 6 |
| Abstract | |
Sporotrichosis has emerged as the main subcutaneous mycosis of humans and animals around the world. With particular differences in frequency, the major species includes Sporothrix brasiliensis, S.schenckii, S.globosa and S.luriei. In Brazil, the main aspect of this epidemic is based on the zoonotic transmission through the scratches and bites of diseased cats contaminated with S.brasiliensis. Areas free of feline sporotrichosis are poorly characterised in Brazil. We investigated by molecular tools the epidemiology of human sporotrichosis in the Espirito Santo (ES) state, an area adjacent to Rio de Janeiro where is the epicentre of the long-lasting outbreak of cat-transmitted sporotrichosis. The human cases in the ES state reveal the prevalence of classical transmission types where subjects are mainly infected by accidental traumatic inoculation during manipulation of contaminated plant material. In agreement with an environmental source, Sporothrix schenckii was the major aetiological agent in the classical transmission. Unlike Rio de Janeiro, this study shows that cat-transmitted epidemic in Espirito Santo is still scanty, although the geographic proximity and similar climatic features. Sporothrix brasiliensis was the agent in the feline-transmitted cases. Sporothrix globosa was isolated from a patient with fixed cutaneous lesions that did not report any contact with diseased animals. In conclusion, beyond the borders of Rio de Janeiro epidemic, agents of sporotrichosis in Espirito Santo show a scattered occurrence with high species diversity. (AU) | |
| FAPESP's process: | 11/07350-1 - Biology of Sporothrix schenckii complex: Analysis of molecular and proteomics markers, and the role of antigenic and antifungal molecules in sporotrichosis |
| Grantee: | Anderson Messias Rodrigues |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/54024-2 - Molecular biology and proteomics of medically interesting fungi: Paracoccidioides brasiliensis and Sporothrix schenckii |
| Grantee: | Zoilo Pires de Camargo |
| Support Opportunities: | Research Projects - Thematic Grants |