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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The role of nicotine, cotinine and caffeine on the electrochemical behavior and bacterial colonization to cp-Ti

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Barao, Valentim A. R. [1] ; Ricomini-Filho, Antonio P. [2] ; Faverani, Leonardo P. [3] ; Del Bel Cury, Altair A. [1] ; Sukotjo, Cortino ; Monteiro, Douglas R. [3] ; Yuan, Judy Chia-Chun [4] ; Mathew, Mathew T. [5] ; do Amaral, Regiane C. [6] ; Mesquita, Marcelo E. [1] ; da Silva, Wander J. [1] ; Assuncao, Wirley G. [3]
Total Authors: 12
Affiliation:
[1] Univ Campinas UNICAMP, Piracicaba Dent Sch, Dept Prosthodont & Periodontol, BR-13414903 Sao Paulo - Brazil
[2] Univ Campinas UNICAMP, Piracicaba Dent Sch, Dept Physiol Sci, BR-13414903 Sao Paulo - Brazil
[3] Univ Estadual Paulista UNESP, Dept Dent Mat & Prosthodont, Aracatuba Dent Sch, BR-16015050 Sao Paulo - Brazil
[4] Univ Illinois, Coll Dent, Dept Restorat Dent, Chicago, IL 60612 - USA
[5] Rush Univ, Dept Orthoped Surg, Med Ctr, Chicago, IL 60612 - USA
[6] Univ Campinas UNICAMP, Dept Publ Hlth, Piracicaba Dent Sch, BR-13414903 Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: Materials Science & Engineering C-Materials for Biological Applications; v. 56, p. 114-124, NOV 1 2015.
Web of Science Citations: 17
Abstract

Although smoking promotes deleterious effect to bone healing, there is a lack of study investigating its role on the implant structure and biofilm growth. We hypothesized that nicotine, cotinine and caffeine would impair the corrosion resistance of commercially-pure titanium (cp-Ti) and would enhance Streptococcus sanguinis biofilm growth. Neither the smoking products nor the caffeine affected the corrosion tendency (P>.05) and the oxide layer resistance (P=.762) of cp-Ti. Lower capacitance values were noted in the presence of nicotine (P=.001) and cotinine (P=.0006). SEM showed no pitting corrosion, and the EDS spectra did not differ among groups. Nicotine (300 mu g/mL) induced higher surface roughness (P=.03) and greater surface change of cp-Ti. Nicotine at 3 mu g/ml, and cotinine at 03 and 3 mu g/mL increased the number of viable cells (P<.05). Biofilm exposed to nicotine (03,3 and 30 mu g/mL) (P=.025, .030, .040, respectively) and cotinine (3 and 30 mu g/mL) (P=.027, .049, respectively) enhanced carbohydrate content. Biofilm biomass and protein content were similar among groups (P>.05). These findings suggest a greater biofilm accumulation in smokers, a risk factor that may lead to peri-implantitis. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 11/20021-7 - The role of nicotine, cotinine and caffeine on the electrochemical behavior and bacterial colonization to cpTi. an in vitro study
Grantee:Wirley Goncalves Assuncao
Support Opportunities: Regular Research Grants
FAPESP's process: 11/20017-0 - The Role of Nicotine, Cotinine and Caffeine on the Electrochemical Behavior and Bacterial Colonization to cpTi. An in vitro study.
Grantee:Valentim Adelino Ricardo Barão
Support Opportunities: Scholarships in Brazil - Post-Doctoral