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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Contact with Fluoride-Releasing Restorative Materials Can Arrest Simulated Approximal Caries Lesion

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Brandao Guglielmi, Camila de Almeida [1] ; Bissoto Calvo, Ana Flavia [1] ; Tedesco, Tamara Kerber [1] ; Mendes, Fausto Medeiros [1] ; Raggio, Daniela Procida [1]
Total Authors: 5
[1] Univ Sao Paulo, Dept Orthodont & Pediat Dent, Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Journal of Nanomaterials; 2015.
Web of Science Citations: 0

Previous studies have suggested that the presence of white-spot lesion is very probable when adjacent surface is affected by cavitated lesions. This study evaluated the potential of different fluoride-releasing restorative materials in arresting enamel white-spot lesions in approximal surface in contact with them, in vitro (I) and in situ (II). White-spot lesions were formed in 240 primary enamel specimens via pH-cycling. They were put in contact with cylindrical blocks of 6 materials (n = 20): composite resin, 2 high-viscous glass ionomer cements (HVGIC), resin-modified GIC, resin-modified nanoionomer, and polyacid-modified resin. In both studies I and II, these settings were designed to simulate the contact point between the restoration and simulated approximal lesion. For study I, they were subjected to a new pH-cycling cariogenic challenge for 7 or 14 days (n = 10). For study II, a randomized double-blind in situ design was conducted in two phases (7/14 days) to promote cariogenic challenge. At the end of both studies, specimens were collected for mineral analysis by cross-sectional microhardness. Higher mineral loss was observed for lesions in contact with resin (p < 0.001). HVGICs were the most efficient in preventing mineral loss, whereas other materials presented an intermediate behavior. It is concluded that fluoride-releasing materials can moderately reduce white-spot lesions progression, and HVGIC can arrest enamel lesion in approximal surface in contact with them. (AU)

FAPESP's process: 10/16120-7 - In vitro and in situ remineralization of approximal lesions in contact with different dental materials in primary teeth
Grantee:Daniela Prócida Raggio
Support Opportunities: Regular Research Grants