| Full text | |
| Author(s): |
Pilli, Ronaldo Aloise
[1]
;
Toneto Novaes, Luiz Fernando
[1]
;
Teixeira Carneiro, Vania Maria
[1]
;
Drekener, Roberta Lopes
[1]
;
Avila, Carolina Martins
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Estadual Campinas, UNICAMP, Inst Chem, Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | CURRENT ORGANIC SYNTHESIS; v. 12, n. 5, p. 523-529, 2015. |
| Web of Science Citations: | 2 |
| Abstract | |
Cryptomoscatones D1 and D2, dihydropyranones isolated from C. mandiocanna, had their stereochemistry solved after total syntheses and comparison of spectroscopic data of natural and synthetic samples. Natural dihydropyranones coibacins A and B, metabolites isolated from marine cyanobacterium cf. Oscillatoria sp, which display antileishmanial activity and anti-inflammatory properties, were synthesized and had their absolute configuration determined. Our efforts towards the synthesis of cryptomoscatone E3, natural dihydropyranone with unknown absolute configuration, are also discussed. (AU) | |
| FAPESP's process: | 11/00457-5 - Synthesis of Dihydropyranones, evaluation of the inhibitory activity of CDC25 and cytotoxicity in tumor cells and structural studies |
| Grantee: | Vânia Maria Teixeira Carneiro |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 09/51602-5 - Chemical biology: new natural and synthetic molecular targets against cancer, structural studies, biological evaluation and mode of action |
| Grantee: | Ronaldo Aloise Pilli |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 10/08673-6 - Studies toward the Synthesis of Analogues of Fostriecin and Total Synthesis and Structural Elucidation of Coibacinas A and B |
| Grantee: | Carolina Martins Avila de Sant'Ana |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 05/52976-5 - Estudos sinteticos visando a sintese e determinacao estrutural das an guinomicinas c e d e estudos sinteticos visando a sintese e determina cao estrutural da criptomoscatona d2 e epimero em c2 |
| Grantee: | Roberta Lopes Drekener |
| Support Opportunities: | Scholarships in Brazil - Doctorate |