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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of 1,3,4-oxadiazole derivatives from alpha-amino acid and acyl hydrazides under thermal heating or microwave irradiation conditions

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Author(s):
Dornelles, Luciano [1] ; Rodrigues, Oscar E. D. [1] ; Heck, Elisiane F. [1] ; Bender, Caroline R. [1] ; Cansian, Mariane B. [1] ; Schwab, Ricardo S. [2] ; Severo Filho, Wolmar A. [3]
Total Authors: 7
Affiliation:
[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS - Brazil
[2] Univ Fed Sao Carlos, Dept Quim, BR-1356590 Sao Carlos, SP - Brazil
[3] Univ Santa Cruz do Sul, Dept Quim & Fis, BR-96815900 Santa Cruz Do Sul, RS - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ARKIVOC; n. 7, p. 131-144, 2015.
Web of Science Citations: 2
Abstract

A series of new 2,5-disubstituted 1,3,4-oxadiazoles was synthesized under conventional thermal heating and microwave irradiation conditions through the reaction of acyl hydrazides with N-protected a-amino acid in presence of a small amount of POCl3. Heterocycles were obtained in moderate to good yields and in relatively short reaction times. (AU)

FAPESP's process: 13/06558-3 - Asymmetric catalysis: preparation of chiral alcohols and their derivatives from highly functionalized organozinc reagents and application of new chiral ligands supported on magnetic nanoparticles
Grantee:Ricardo Samuel Schwab
Support type: Regular Research Grants