Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of 1,3,4-oxadiazole derivatives from alpha-amino acid and acyl hydrazides under thermal heating or microwave irradiation conditions

Full text
Dornelles, Luciano [1] ; Rodrigues, Oscar E. D. [1] ; Heck, Elisiane F. [1] ; Bender, Caroline R. [1] ; Cansian, Mariane B. [1] ; Schwab, Ricardo S. [2] ; Severo Filho, Wolmar A. [3]
Total Authors: 7
[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS - Brazil
[2] Univ Fed Sao Carlos, Dept Quim, BR-1356590 Sao Carlos, SP - Brazil
[3] Univ Santa Cruz do Sul, Dept Quim & Fis, BR-96815900 Santa Cruz Do Sul, RS - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ARKIVOC; n. 7, p. 131-144, 2015.
Web of Science Citations: 2

A series of new 2,5-disubstituted 1,3,4-oxadiazoles was synthesized under conventional thermal heating and microwave irradiation conditions through the reaction of acyl hydrazides with N-protected a-amino acid in presence of a small amount of POCl3. Heterocycles were obtained in moderate to good yields and in relatively short reaction times. (AU)

FAPESP's process: 13/06558-3 - Asymmetric catalysis: preparation of chiral alcohols and their derivatives from highly functionalized organozinc reagents and application of new chiral ligands supported on magnetic nanoparticles
Grantee:Ricardo Samuel Schwab
Support type: Regular Research Grants