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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Variability in Obstacle Clearance May (Not) Indicate Cognitive Disorders in Alzheimer Disease

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Barbieri, Fabio A. [1, 2] ; Simieli, Lucas [1] ; Orcioli-Silva, Diego [1] ; Vitorio, Rodrigo [1] ; Stella, Florindo [1, 3] ; Gobbi, Lilian T. Bucken [1]
Total Authors: 6
[1] Univ Estadual Paulista, UNESP, LEPLO, Rio Claro, SP - Brazil
[2] Univ Estadual Paulista, UNESP, LIVIA, BR-17033360 Bauru, SP - Brazil
[3] Sao Paulo State Univ Campinas, UNICAMP, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Alzheimer Disease & Associated Disorders; v. 29, n. 4, p. 307-311, OCT-DEC 2015.
Web of Science Citations: 2

The aim of this study was to investigate obstacle clearance and its variability in individuals with Alzheimer dementia (AD) as well as healthy elderly individuals while they approached and crossed an obstacle in their path. Fifteen people with AD and 15 age-matched/sex-matched healthy individuals (control group) participated in this study. Clinical assessment of both groups was performed by a neuropsychiatrist. Spatial-temporal parameters of 5 trials of unobstructed walking and 5 trials of obstacle crossing during walking (approach and crossing phases) were measured using a 3-dimensional optoelectronic system. The results indicated that individuals with AD showed higher variability in the approach phase for stride length and the horizontal distance from their trailing limb foot to the obstacle. However, their gait variability in the crossing phase was similar to the control group. In addition, the individuals with AD were found to walk slowly and with a short stride length in both conditions. In conclusion, individuals with AD had increased gait variability while approaching an obstacle during walking, indicating a deficit in planning to avoid obstacles that could be related to cognitive disorders. However, gait variability during the crossing phase may not be indicative of cognitive disorders in AD. (AU)

FAPESP's process: 09/54275-5 - Influence of dual tasks in free and adaptive walking of patients with Alzheimer's dementia
Grantee:Lucas Simieli
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 11/00414-4 - Effect of physical activity program in spatio-temporal parameters of the gait in elderly with Alzheimer's Disease
Grantee:Diego Orcioli da Silva
Support type: Scholarships in Brazil - Scientific Initiation