Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Physiologic, health, and production responses of dairy cows supplemented with an immunomodulatory feed ingredient during the transition period

Full text
Brandao, A. P. [1, 2] ; Cooke, R. F. [1] ; Corra, F. N. [2] ; Piccolo, M. B. [2] ; Gennari, R. [2] ; Leiva, T. [2] ; Vasconcelos, J. L. M. [2]
Total Authors: 7
[1] Oregon State Univ, Eastern Oregon Agr Res Ctr, Burns, OR 97720 - USA
[2] Sao Paulo State Univ, Dept Anim Prod, BR-18168000 Botucatu, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF DAIRY SCIENCE; v. 99, n. 7, p. 5562-5572, JUL 2016.
Web of Science Citations: 16

This study compared physiological, health, and productive parameters in dairy cows supplemented or not with Omnigen-AF (OMN, Phibro Animal Health, Teaneck, NJ) during the transition period. Thirty-eight nonlactating, multiparous, pregnant Holstein x Gir cows were ranked by body weight (BW) and body condition score (BCS), and assigned to receive (in 19) or not (CON; n = 19) OMN at 56 g/cow daily (as-fed basis) beginning 35 d before expected date of calving. Before calving, cows were maintained in single drylot pen with ad libitum access to corn silage, and received (as-fed basis) 3 kg/cow daily of a concentrate. After calving, cows were moved to an adjacent drylot pen, milked twice daily, offered (as-fed basis) 35 kg/cow daily of corn silage, and individually received a concentrate formulated to meet their nutritional requirements after both milkings. Cows received OMN individually as top-dressing in the morning concentrate feeding. Before calving, cow BW and RCS were recorded weekly and blood samples were collected every 5 d beginning on d 35 relative to expected calving date. After calving and until 46 d in milk, BW and BCS were recorded weekly, individual milk production was recorded, and milk samples were collected daily for total solids and somatic cell count analyses. Blood was sampled daily from 0 to 7 d in milk, every other day from 9 to 21 d in milk, and every 5 d from 26 to 46 d in milk. On 30 and 46 d in milk, cows were evaluated for endometritis via cytobrush technique, based on % of polymorphonuclear (PMN) cells in 100 total cell count (PMN I endow trial cells). On 48.7 +/- 1.6 d in milk, 9 cows/treatment received a lipopolysaccharide (LPS) injection (0.25 mu g/kg of BW), and blood was sampled hourly from 2 to 8 h, at 12-h intervals from 12 to 72 h, and at 24-h intervals form 96 to 120 h relative to LPS administration. No treatment differences were detected on BW, BCS, serum concentrations of cortisol, fatty acids, insulin, glucose, haptoglobin, cortisol, and insulin-like growth factor-I. Cows receiving OMN had greater milk yield (30.3 vs. 27.1 kg/d) and percentage of PMN cells in endometrial cell population (12.2 vs. 3.9%) compared with CON cows. After LPS administration, cows receiving OMN had greater mean serum haptoglobin (212 vs. 94 mu g/mL), as well as greater serum concentration of tumor necrosis factor a at 1, 2, and 3 h relative to LPS injection compared with CON cows. In conclusion, OMN supplementation during the transition period enhanced innate immunity parameters and increased milk production in dairy cows. (AU)

FAPESP's process: 15/05536-1 - Omnigen-AF® supplementation for dairy cows during transition period and early lactation: metabolic and immune impacts
Grantee:Alice Poggi Brandão
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 14/14512-6 - Effect of energy sources (starch, pectin or fat) and chromium supplementation, on high energy diet, on serum concentrations of glucose, insulin, and non-esterified fatty acids on lactating dairy cows
Grantee:Tiago Leiva
Support Opportunities: Scholarships in Brazil - Doctorate