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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis

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da Silva Batista, Luis Fabio [1, 2] ; Ribeiro da Matta, Vania Lucia [1] ; Tomokane, Thaise Yumie [1] ; Pacheco, Accio Duarte [3] ; Silveira, Fernando Tobias [4, 5] ; Rossi, Claudio Nazaretian [6] ; Marcondes, Mary [3] ; Laurenti, Marcia Dalastra [1]
Total Authors: 8
[1] Univ Sao Paulo, Fac Med, Lab Patol Molestias Infecciosas, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Patol, Sao Paulo, SP - Brazil
[3] Univ Estadual Sao Paulo, Fac Med Vet, Dept Clin Cirurgia & Reprod Anim, Sao Paulo - Brazil
[4] Fed Univ Para, Nucleo Med Trop, Belem, Para - Brazil
[5] Minist Saude, Inst Evandro Chagas, Ananindeua, Para - Brazil
[6] Univ Paulista, Inst Ciencias Saude, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 49, n. 3, p. 361-364, MAY-JUN 2016.
Web of Science Citations: 2

Introduction: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. Methods: Immunoglobulin G (IgG) anti-Lu longipalpis saliva and-L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. Results: Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. Conclusions: Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas. (AU)

FAPESP's process: 12/50285-9 - Clinical, immunological features and its correlation with genetic markers in canine visceral leishmaniasis
Grantee:Marcia Dalastra Laurenti
Support type: Regular Research Grants