Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Comparative Study of Chemical Composition and Biological Activity of Yellow, Green, Brown, and Red Brazilian Propolis

Full text
Author(s):
Show less -
Machado, Christiane Schineider ; Mokochinski, Joao Benhur ; de Lira, Tatiana Onofre ; Evangelista de Oliveira, Fatima de Cassia ; Cardoso, Magda Vieira ; Ferreira, Roseane Guimaraes ; Helena Frankland Sawaya, Alexandra Christine ; Ferreira, Antonio Gilberto ; Pessoa, Claudia ; Cuesta-Rubio, Osmany ; Monteiro, Marta Chagas ; de Campos, Monica Soares ; Torres, Yohandra Reyes
Total Authors: 13
Document type: Journal article
Source: Evidence-based Complementary and Alternative Medicine; 2016.
Web of Science Citations: 7
Abstract

The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing H-1-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated. (AU)

FAPESP's process: 13/21306-0 - DEVELOPMENT OF ANALYTICAL METHODS BY UPLC-MS FOR THE METABOLOMIC STUDY OF TWO SPECIES OF EUCALYPTUS EXPOSED TO CHANGES IN TEMPERATURE AND CONCENTRATION OF CO2
Grantee:João Benhur Mokochinski
Support type: Scholarships in Brazil - Doctorate