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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Influence of Titanium Dioxide on Diamond-Like Carbon Biocompatibility for Dental Applications

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Wachesk, C. C. ; Trava-Airoldi, V. J. ; Da-Silva, N. S. ; Lobo, A. O. ; Marciano, F. R.
Total Authors: 5
Document type: Journal article
Source: Journal of Nanomaterials; 2016.
Web of Science Citations: 2

The physical and chemical characteristics of diamond-like carbon (DLC) films make them suitable for implantable medical and odontological interests. Despite their good interactions with biological environment, incorporated nanoparticles can significantly enhance DLC properties. This manuscript studies the potential of titanium dioxide (TiO2) incorporated-DLC films in dental applications. In this scene, both osteoblasts attachment and spreading on the coatings and their corrosion characteristics in artificial saliva were investigated. The films were grown on 304 stainless steel substrates using plasma enhanced chemical vapor deposition. Raman scattering spectroscopy characterized the film structure. As the concentration of TiO2 increased, the films increased the osteoblast viability (MTT assay), becoming more thermodynamically favorable to cell spreading (W-Ad values became more negative). The increasing number of osteoblast nuclei indicates a higher adhesion between the cells and the films. The potentiodynamic polarization test in artificial saliva shows an increase in corrosion protection when TiO2 are present. These results show the potential use of TiO2-DLC films in implantable surfaces. (AU)

FAPESP's process: 11/20345-7 - Study of nanoparticle-incorporated diamond-like carbon films for biomedical applications
Grantee:Fernanda Roberta Marciano
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 13/20054-8 - Studies of adhesion, proliferation and cell death in the interaction of cells with nanostructured materials
Grantee:Newton Soares da Silva
Support Opportunities: Regular Research Grants
FAPESP's process: 12/15857-1 - Scientific studies and innovation application on CVD diamond, DLC and carbon nanostructures obtained by chemical vapor deposition technique
Grantee:Vladimir Jesus Trava-Airoldi
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 11/17877-7 - Development of new polymeric scaffolds by electrospinning technique with incorporation of vertically aligned carbon nanotubes and nanohidroxyapatite for bone tissue regeneration
Grantee:Anderson de Oliveira Lobo
Support Opportunities: Research Grants - Young Investigators Grants