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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Spectroelectrochemical study of acetylsalicylic acid in neutral medium and its quantification in clinical and environmental samples

Full text
Author(s):
do Prado, Thiago M. ; Cincotto, Fernando H. ; Machado, Sergio A. S.
Total Authors: 3
Document type: Journal article
Source: Electrochimica Acta; v. 233, p. 105-112, APR 10 2017.
Web of Science Citations: 3
Abstract

This paper describes the application of simultaneous electrochemical reduction and UV absorbance methods (spectroelectrochemical techniques, highlighting the derivative linear scan voltabsorptometry) in the determination of acetylsalicylic acid in neutral medium, using a platinum gauze electrode modified with nanocomposite of reduced graphene oxide with gold nanoparticles (rGO/AuNPs). In solution, the process involving one electron to produce the radical acetylsalicylate was observed. Such mechanism was confirmed by electronic paramagnetic resonance (EPR). This study demonstrated that the voltabsorptometric sensor is highly sensitive for the determination of acetylsalicylic acid, with a limit of detection of 0.26 mu mol L (1). No significant interference was detected for ascorbic and uric acid in the determination of acetylsalicylic acid. The platinum gauze with rGO/AuNPs modified electrode device was successfully applied in the acetylsalicylic acid determination in an environmental samples (wastewater) and clinical (tablets of drugs and human urine) samples, and is a promising platform for a simple, rapid, direct and very sensitive analysis of acetylsalicylic acid. (C) 2017 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 13/17053-0 - Development of an electroanalytical methodology for selective doping of electrodeposited selenium semiconducting films based in the underpotential deposition
Grantee:Sergio Antonio Spinola Machado
Support Opportunities: Regular Research Grants
FAPESP's process: 16/16565-5 - Development of ultra-sensitive methods for RNA detection for the diagnosis of Head and Neck Cancer
Grantee:Fernando Henrique Cincotto
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 06/53266-4 - Chemistry, photochemistry and biological applications of ruthenium complexes with nitric oxide and related species. From solution to materials
Grantee:Elia Tfouni
Support Opportunities: Research Projects - Thematic Grants