Hypoxia during embryonic development increases energy metabolism in normoxic juvenile chicks

Author(s)

do Amaral-Silva, Lara ; Scarpellini, Carolina da S. ; Toro-Velasquez, Paula Andrea ; Fernandes, Marcia H. M. R. ; Gargaglioni, Luciane H. ; Bicego, Kenia C.

• Document type: Journal article
• Source: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY; v. 207, p. 93-99, MAY 2017.
• Web of Science Citations: 2

Abstract

Environmental changes during perinatal development can affect the postnatal life. In this sense, chicken embryos that experience low levels of O-2 over a specific phase of incubation can have their tissue growth reduced and the ventilatory response to hypoxia blunted, at least until hatching. Additionally, exposure to low level of 02 after birth reduces the thermogenesis as well. In the present study, we tested the hypothesis that hypoxia over the third week of incubation affects the thermoregulation of juvenile chicks at an age when thermogenesis is already expected to be well-developed. To this end, we measured body temperature (Tb) and oxygen consumption (V0(2)) under acute hypoxia or different ambient temperatures (Ta) of 1 and 10 day-old chicks that have been exposed to 21%O-2 for entire incubation (Nx) or to 15% O-2 in the last week of incubation (Hx). We also assessed the thermal preference under normoxia or acute hypoxia of the older chicks from both incubation groups in a thermocline. Hypoxia over incubation reduced growth but did not affect the cold-induced thermogenesis in hatchlings. Regarding the juvenile Hx, present data indicate a catch up growth with higher resting V0(2), a thermal preference for warmer Tas and a possible higher thermal conductance. In conclusion, our results show that hypoxia over the third week of incubation can affect the thermoregulation at least until 10 days after hatch in chickens. (C) 2017 Elsevier Inc All rights reserved. (AU)

• FAPESP's process: 11/19131-2 - Role of hypothalamic TRPV4 channels in activation/inhibition of autonomic thermoeffectors during fever and endotoxemic chock
• Grantee: Carolina da Silveira Scarpellini
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 10/20285-1 - Exposure to hypoxia during incubation and its role in the thermal preference and metabolic curve of 1-2 week old broiler chicks
• Grantee: Kênia Cardoso Bícego
• Support Opportunities: Regular Research Grants
• FAPESP's process: 14/01861-2 - Effect of hypoxia during late phase of incubation on post-hatching lung structures in broiler
• Grantee: Lara do Amaral Silva
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 11/07509-0 - Exposure to hypoxia during incubation and its influence on thermal preference and metabolic curve of broiler chicks during the first week post-hatching
• Grantee: Paula Andrea Toro Velásquez
• Support Opportunities: Scholarships in Brazil - Doctorate