Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Nanodiamonds stabilized in dihexadecyl phosphate film for electrochemical study and quantification of codeine in biological and pharmaceutical samples

Full text
Author(s):
Simioni, Natalia Bortolucci ; Oliveira, Geiser Gabriel ; Vicentini, Fernando Campanha ; Lanza, Marcos R. V. ; Janegitz, Bruno C. ; Fatibello-Filho, Orlando
Total Authors: 6
Document type: Journal article
Source: DIAMOND AND RELATED MATERIALS; v. 74, p. 191-196, APR 2017.
Web of Science Citations: 15
Abstract

A new architecture for a sensor and a voltammetric procedure were proposed, using a glassy carbon electrode modified with nanodiamonds and dihexadecyl phosphate for determination of codeine (COD) in pharmaceutical and biological fluid samples. Square-wave voltammetry (SWV) was used and the relevant experimental parameters were optimized. Under optimal experimental conditions, the analytical curve presented a linear concentration range from 0.299 to 10.8 mu mol L-1, and a limit of detection of 54.5 nmol L-1. The proposed voltammetric method was used for COD determination in commercial pharmaceutical and biological fluid samples such as urine and human serum with satisfactory results. (C) 2017 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 15/19099-2 - Development of electrochemical sensors and biosensors for different analytical purposes
Grantee:Bruno Campos Janegitz
Support type: Regular Research Grants
FAPESP's process: 13/16770-0 - Sensors development based on polymeric films and nanomaterials for several analytical applications
Grantee:Fernando Campanhã Vicentini
Support type: Scholarships in Brazil - Post-Doctorate