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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Orbital apex syndrome affecting head and neck cancer patients: A case series

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Prado-Ribeiro, Ana-Carolina ; Luiz, Ana-Claudia ; Montezuma, Marco-Aurelio ; Mak, Milena-Perez ; Santos-Silva, Alan-Roger ; Brandao, Thais-Bianca
Total Authors: 6
Document type: Journal article
Source: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL; v. 22, n. 3, p. E354-E358, MAY 1 2017.
Web of Science Citations: 1

Background: Orbital apex syndrome (OAS) is a complex and uncommon disorder that typically damages multiple cranial nerves in association with optic nerve dysfunction. OAS is associated with several different pathologies, however; only a few cases have been reported in association with head and neck cancer (HNC) so far. Material and Methods: A case series of HNC patients diagnosed with OAS is described including clinicopathological data, image findings, and disease outcome. Results: Ptosis and diplopia were diagnosed in four male patients with mean age of 61.2 years who were undergoing treatment for late-stage carcinomas of the tongue, larynx, and nasopharynx, eventually leading to the diagnosis of OAS. The mean overall survival rate after the diagnosis of OAS was 9.5 months. Conclusions: The current study reinforces evidence that OAS indicates poor prognosis and highlights the importance of early diagnosis. (AU)

FAPESP's process: 13/18402-8 - Evaluation of the direct effects of radiation on the enamel, dentin and dental pulp of head and neck cancer patients
Grantee:Alan Roger dos Santos Silva
Support type: Regular Research Grants
FAPESP's process: 12/06138-1 - A prospective study of radiation-induced trismus in patients with oral squamous cell carcinoma
Grantee:Ana Carolina Prado Ribeiro e Silva
Support type: Regular Research Grants