Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Placebo in sports nutrition: a proof-of-principle study involving caffeine supplementation

Full text
Show less -
Saunders, B. [1] ; de Oliveira, L. F. [1] ; da Silva, R. P. [1] ; de Salles Painelli, V. [1] ; Goncalves, L. S. [1] ; Yamaguchi, G. [1] ; Mutti, T. [1] ; Maciel, E. [2] ; Roschel, H. [1, 2] ; Artioli, G. G. [1, 2] ; Gualano, B. [1, 2]
Total Authors: 11
[1] Univ Sao Paulo, Appl Physiol & Nutr Res Grp, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Rheumatol Div, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS; v. 27, n. 11, p. 1240-1247, NOV 2017.
Web of Science Citations: 35

We investigated the effects of supplement identification on exercise performance with caffeine supplementation. Forty-two trained cyclists (age 37 +/- 8years, body mass {[}BM] 74.3 +/- 8.4kg, height 1.76 +/- 0.06m, maximum oxygen uptake 50.0 +/- 6.8mL/kg/min) performed a similar to 30min cycling time-trial 1h following either 6mg/kgBM caffeine (CAF) or placebo (PLA) supplementation and one control (CON) session without supplementation. Participants identified which supplement they believed they had ingested (caffeine, placebo, don't know) pre- and post-exercise. Subsequently, participants were allocated to subgroups for analysis according to their identifications. Overall and subgroup analyses were performed using mixed-model and magnitude-based inference analyses. Caffeine improved performance vs PLA and CON (P0.001). Correct pre- and post-exercise identification of caffeine in CAF improved exercise performance (+4.8 and +6.5%) vs CON, with slightly greater relative increases than the overall effect of caffeine (+4.1%). Performance was not different between PLA and CON within subgroups (all P>0.05), although there was a tendency toward improved performance when participants believed they had ingested caffeine post-exercise (P=0.06; 87% likely beneficial). Participants who correctly identified placebo in PLA showed possible harmful effects on performance compared to CON. Supplement identification appeared to influence exercise outcome and may be a source of bias in sports nutrition. (AU)

FAPESP's process: 11/19513-2 - Effects of Chronic Beta-Alanine Supplementation with and without Acute Sodium Bicarbonate Ingestion on Peak Muscle Carnosine Concentration, Washout and High-Intensity Exercise Performance
Grantee:Bryan Saunders
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/04806-0 - Effects of 12 weeks of high-intensity intermittent training on intramuscular carnosine concentrations
Grantee:Vitor de Salles Painelli
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 13/14746-4 - Carnosine metabolism in skeletal muscle: a multi-approach study
Grantee:Bruno Gualano
Support type: Research Projects - Thematic Grants
FAPESP's process: 14/11948-8 - Life without carnosine: development and characterization of a KO rat model for studying the physiological role of carnosine and its implications to physical exercise and muscle metabolism
Grantee:Guilherme Giannini Artioli
Support type: Research Grants - Young Investigators Grants