| Full text | |
| Author(s): |
Ybarra, Marina
[1]
;
Franco, Ruth Rocha
[1]
;
Cominato, Louise
[1]
;
Sampaio, Raissa Beltrao
[1]
;
Sucena da Rocha, Silvia Maria
[2]
;
Damiani, Durval
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Pediat Endocrinol Unit, Inst Crianca, Hosp Clin, Fac Med, Sao Paulo - Brazil
[2] Univ Sao Paulo, Pediat Radiol Unit, Inst Crianca, Hosp Clin, Fac Med, Sao Paulo - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | Gynecological Endocrinology; v. 34, n. 1, p. 45-48, 2018. |
| Web of Science Citations: | 4 |
| Abstract | |
Background and aims: In adolescence and obesity, the pathophysiology of polycystic ovary syndrome (PCOS) is very difficult to distinguish. We aimed to assess the diagnosis of PCOS in the population of obese adolescent. Methods: Cross-sectional study. Setting: Pediatric Endocrinology Weight and Management Clinic from Children's Institute, Sao Paulo, Brazil. Participants: Forty-nine post-menarcheal obese adolescents with mean age of 14.7 years. Interventions: Anthropometric assessment and review of medical records were done. Clinical and laboratory hyperandrogenism were quantified using Ferriman-Gallwey index and androgenic dosages, respectively. Ovarian morphology was evaluated through suprapubic ultrasonography. Results: By the 2015 Witchel et al. guideline for PCOS in adolescence, 18.4% were diagnosed as having PCOS. When assessed by Rotterdam, Androgen Excess and PCOS Society, and American National Institute of Health criteria's, 26.4%, 22.4%, and 20.4% had PCOS, respectively. Irregular menstrual cycles were found in 65.3% of patients. Clinical hyperandrogenism was observed in 16.3% of girls and 18.4% had elevated serum androgen values. Suprapubic ultrasonography revealed enlarged ovaries in 18.4% of the adolescents. Conclusions: PCOS in all-comers obese adolescents from a Weight and Management Clinic in a quaternary hospital is more frequent when compared to adult women showed in the literature. (AU) | |
| FAPESP's process: | 14/11200-3 - Evaluation of the prevalence and characteristics of polycystic ovary syndrome in obese adolescents |
| Grantee: | Marina Pereira Ybarra Martins de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Master |