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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Kavalactones and Benzoic Acid Derivatives from Leaves of Piper fuligineum Kunth (Piperaceae)

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Author(s):
Bruna F. Mazzeu [1] ; Lidiane G. Felippe [2] ; Fernando Cotinguiba [3] ; Massuo J. Kato [4] ; Maysa Furlan [5]
Total Authors: 5
Affiliation:
[1] Universidade Estadual Paulista. Instituto de Química - Brasil
[2] Universidade Estadual Paulista. Instituto de Química - Brasil
[3] Universidade Federal do Rio de Janeiro. Instituto de Pesquisas de Produtos Naturais - Brasil
[4] Universidade de São Paulo. Instituto de Química - Brasil
[5] Universidade Estadual Paulista. Instituto de Química - Brasil
Total Affiliations: 5
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 29, n. 6, p. 1286-1290, 2018-06-00.
Abstract

The known kavalactones (E)-4-methoxy-6-styryl-2H-pyran-2-one, 4-methoxy-6-(3-phenyloxiran-2-yl)-2H-pyran-2-one, 6-(1,2-dihydroxy-2-phenylethyl)-4-methoxy-2H-pyran-2-one, the three benzoic acid derivatives methyl-4-methoxy-3-(3'-methyl-2'-butenyl)benzoate and methyl 2,2-dimethyl-4-oxochroman-6-carboxylate, and a new methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate were isolated from the ethanolic extract of Piper fuligineum. The structures of these compounds were determined by using a combination of spectroscopic methods, including 1D- and 2D-nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. This is the first report of the chemical study of P. fuligineum, and the methyl 4-methoxy-3-(3-methylbut-2-enoyl)benzoate is described as a new natural product. (AU)

FAPESP's process: 14/50316-7 - Dimensions US-Biota São Paulo: Chemically mediated multi-trophic interaction diversity across tropical gradients
Grantee:Massuo Jorge Kato
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 11/16752-6 - Study on the structural and biosynthetic Piper Fuligineum Kunth (Piperaceae)
Grantee:Bruna Fonseca Mazzeu
Support type: Scholarships in Brazil - Master
FAPESP's process: 13/15306-8 - Studies concerning the biosynthesis of quinonemethides triterpenes by metabolic engineering: evaluation of the micro- and macromolecular metabolic flow of heterologous system by proteomics and metabolomics techniques.
Grantee:Lidiane Gaspareto Felippe
Support type: Scholarships in Brazil - Post-Doctorate