Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review

Full text
Pascoli, Monica [1] ; de Lima, Renata [2] ; Fraceto, Leonardo F. [1]
Total Authors: 3
[1] Sao Paulo State Univ UNESP, Environm Chem, Inst Sci & Technol, Sorocaba - Brazil
[2] Univ Sorocaba, Dept Biotechnol, Sorocaba - Brazil
Total Affiliations: 2
Document type: Review article
Source: FRONTIERS IN CHEMISTRY; v. 6, JAN 25 2018.
Web of Science Citations: 10

Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture. (AU)

FAPESP's process: 15/17120-4 - Toxicity evaluation and biological activity of zein nanoparticles containing the biocide azadirachtin
Grantee:Mônica Pascoli
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 15/15617-9 - Botanical repellents and nanotechnology: development of systems for pest control in agriculture
Grantee:Leonardo Fernandes Fraceto
Support type: Regular Research Grants