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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Beta-defensin genes of the Colubridae snakes Phalotris mertensi, Thamnodynastes hypoconia, and T-strigatus

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de Oliveira, Yago Santana [1] ; Correa, Poliana G. [1] ; Oguiura, Nancy [1]
Total Authors: 3
[1] Inst Butantan, Ecol & Evolut Lab, Ave Dr Vital Brasil 1500, BR-05503900 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Toxicon; v. 146, p. 124-128, MAY 2018.
Web of Science Citations: 0

beta-Defensins are cationic antimicrobial peptides showing little sequence similarity but highly conserved tertiary structure stabilized by a six-cysteines-motif. Using a PCR approach, we described beta-defensin sequences with two exons in three species of Colubridae snakes with high sequence similarity between them. The deduced amino acid sequence presented the characteristics of beta-defensin family. The phylogenetic analysis using beta-defensin coding sequences of different snakes grouped them in two main branches: genes organized in three or two exons. (C) 2018 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 15/00003-5 - Snake genes of venom toxins and b-defensins
Grantee:Nancy Oguiura
Support Opportunities: Regular Research Grants