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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Absolute configurations of griseorhodins A and C

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Author(s):
Ortega, Humberto E. [1] ; Batista, Jr., Joao M. [2] ; Melo, Weilan G. P. [1] ; Clardy, Jon [3] ; Pupo, Monica T. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Fed Univ Sao Carlos UFSCar, Dept Chem, Rod Washington Luis Km 235, BR-13565905 Sao Carlos, SP - Brazil
[3] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 - USA
Total Affiliations: 3
Document type: Journal article
Source: Tetrahedron Letters; v. 58, n. 50, p. 4721-4723, DEC 13 2017.
Web of Science Citations: 4
Abstract

The known antibiotic and cytotoxic compounds griseorhodin A (1) and griseorhodin C (2) were produced in solid culture by Streptomyces puniceus AB10, which was isolated from the leaf-cutter ant Acromyrmex rugosus rugosus. Their absolute configurations were unambiguously established as 6S,6aR,7S,8S and 6R,6aR,7S,8R, respectively, using vibrational circular dichroism (VCD) and density functional theory (DFT) calculations. (C) 2017 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 14/25222-9 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules
Grantee:João Marcos Batista Junior
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 15/01001-6 - Discovering bacterial symbionts diversity associated with ants in different Brazilian biomes
Grantee:Weilan Gomes da Paixão Melo
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/50954-0 - Novel therapeutic agents from the bacterial symbionts of Brazilian invertebrates
Grantee:Mônica Tallarico Pupo
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 15/07089-2 - Vibrational chiroptical spectroscopy for stereochemical characterization of small molecules and macromolecules
Grantee:João Marcos Batista Junior
Support type: Scholarships in Brazil - Young Researchers