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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review

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Moura, Carolina Soares [1] ; Barboza Lollo, Pablo Christiano [2] ; Morato, Priscila Neder [2] ; Amaya-Farfan, Jaime [1]
Total Authors: 4
[1] Univ Estadual Campinas, Fac Food Engn, Dept Food & Nutr, Prot Resources Lab, BR-13083862 Campinas, SP - Brazil
[2] Fed Univ Grande Dourados, Sch Hlth Sci, BR-79825070 Dourados, MS - Brazil
Total Affiliations: 2
Document type: Review article
Source: NUTRIENTS; v. 10, n. 6 JUN 2018.
Web of Science Citations: 8

Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living organisms, has ranged from their chaperone function in nascent proteins to the remedial role following cell stress. As part of the defence system, HSPs guarantee cell tolerance against a variety of stressors, including exercise, oxidative stress, hyper and hypothermia, hyper and hypoxia and improper diets. For the past couple of decades, research on functional foods has revealed a number of substances likely to trigger cell protection through mechanisms that involve the induction of HSP expression. This review will summarize the occurrence of the most easily inducible HSPs and describe the effects of dietary proteins, peptides, amino acids, probiotics, high-fat diets and other food-derived substances reported to induce HSP response in animals and humans studies. Future research may clarify the mechanisms and explore the usefulness of this natural alternative of defense and the modulating mechanism of each substance. (AU)

FAPESP's process: 17/16886-9 - Effect of whey protein intake on heat shock proteins (HSPs) and intestinal microbiot in obese rats induced by cafeteria diet
Grantee:Jaime Amaya Farfan
Support Opportunities: Regular Research Grants
FAPESP's process: 16/06630-4 - Effect of whey protein intake on heat shock proteins (HSPs) in obese rats induced by cafeteria diet
Grantee:Carolina Soares de Moura
Support Opportunities: Scholarships in Brazil - Post-Doctorate