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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

New Genomic Approaches to Enhance Biomass Degradation by the Industrial Fungus Trichoderma reesei

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de Paula, Renato Graciano [1] ; Campos Antonieto, Amanda Cristina [1] ; Costa Ribeiro, Liliane Fraga [1] ; Carraro, Claudia Batista [1] ; Vieira Nogueira, Karoline Maria [1] ; Borges Lopes, Douglas Christian [1] ; Silva, Alinne Costa [1] ; Zerbini, Mariana Taise [1] ; Pedersoli, Wellington Ramos [1] ; Costa, Mariana do Nascimento [1] ; Silva, Roberto Nascimento [1]
Total Authors: 11
[1] Univ Sao Paulo, Ribeirao Preto Med Sch FMRP, Dept Biochem & Immunol, Mol Biotechnol Lab, Ribeirao Preto, SP - Brazil
Total Affiliations: 1
Document type: Review article
Web of Science Citations: 6

The filamentous fungi Trichoderma reesei is one of the most well-studied cellulolytic microorganisms. It is the most important fungus for the industrial production of enzymes to biomass deconstruction being widely used in the biotechnology industry, mainly in the production of biofuels. Here, we performed an analytic review of the holocellulolytic system presented by T. reesei as well as the transcriptional and signaling mechanisms involved with holocellulase expression in this fungus. We also discuss new perspectives about control of secretion and cellulase expression based on RNA-seq and functional characterization data of T. reesei growth in different carbon sources, which comprise glucose, cellulose, sophorose, and sugarcane bagasse. (AU)

FAPESP's process: 17/04206-3 - Elucidation of cellular signaling pathways mediated by protein kinase A (PKA), MAPK and calcium during expression and secretion of cellulases by the fungus Trichoderma reesei
Grantee:Roberto Do Nascimento Silva
Support type: Regular Research Grants
FAPESP's process: 16/23233-9 - Characterization of calcium-dependent signaling pathway in the secretion and cellulase expression by Trichoderma reesei (Hypocrea jecorina
Grantee:Renato Graciano de Paula
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 16/20358-5 - Systems biology analysis of the role of protein kinase a (PKA), in the fungus Trichoderma reesei by phosphoproteomic
Grantee:Liliane Fraga Costa Ribeiro
Support type: Scholarships in Brazil - Post-Doctorate