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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

New sintered wollastonite glass-ceramic for biomedical applications

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Author(s):
Soares, Viviane O. [1, 2] ; Daguano, Juliana K. M. B. [3] ; Lombello, Christiane B. [3] ; Bianchin, Olavo S. [4] ; Goncalves, Livia M. G. [4] ; Zanotto, Edgar D. [4]
Total Authors: 6
Affiliation:
[1] Univ Estadual Maringa, Dept Ciencias, BR-87360000 Goioere, PR - Brazil
[2] Ave Reitor Zeferino Vaz S-N, BR-87360000 Goioere, Parana - Brazil
[3] UFABC, Ctr Engn Modelagem & Ciencias Socials Aplicadas, CECS, BR-09606070 Sdo Bernardo Do Campo, SP - Brazil
[4] Univ Fed Sao Carlos, Dept Engn Mat, Lab Mat Vitreos, Ctr Res Technol & Educ Vitreous Mat LaMaV DEMa UF, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: CERAMICS INTERNATIONAL; v. 44, n. 16, p. 20019-20027, NOV 2018.
Web of Science Citations: 0
Abstract

We developed a new bioactive glass-ceramic (GC) based on the CaO-SiO2-MgO-Na2O-Li2O system. Four glass compositions were formulated by a proprietary software (Reformix) and tested by changing mainly the calcium content (from 20 mol% to 40 mol%) and the minor components-alumina, zirconia and zinc oxide. We produced our GCs using the sinter-crystallization process at different temperatures (800-1000 degrees C) and evaluated the effects of compositional changes on the sintering kinetics, microstructure (residual porosity and crystalline phases), hardness, bending strength and bioactivity. We then followed the hydroxycarbonate apatite (HCA) formation in simulated body fluid by Fourier-transform infrared spectroscopy (FTIR), which revealed the onset of HCA formation after approximately 3 days. These GCs are phosphorus and fluorine free, elements that are present in most bioactive glasses, glass-ceramics and ceramics. Our most bioactive GC has a residual porosity of 9 +/- 1%, hardness of 5.5 +/- 0.3 GPa, 4p-bending strength of 98 +/- 7 MPa and is non-cytotoxic. This combination of good bioactivity and mechanical properties (despite its high porosity) suggests that this new GC could be tested for bone graft implants. (AU)

FAPESP's process: 10/15635-3 - Design of mineralmimetic microstructures to obtain high toughness glass-ceramics for biomedical applications
Grantee:Juliana Kelmy Macário Barboza Daguano
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 12/03072-0 - Development of bioactive glass-ceramics with high fracture toughness
Grantee:Olavo Serafin Bianchin
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 07/08179-9 - Kinetic processes in glasses and glass ceramics
Grantee:Edgar Dutra Zanotto
Support type: Research Projects - Thematic Grants
FAPESP's process: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass
Grantee:Edgar Dutra Zanotto
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 11/22936-2 - High toughness glass-ceramics in the MgO-Al2O3-SiO2 system
Grantee:Lívia Maria Garcia Gonçalves
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 10/18947-6 - Development of High-Toughness glass ceramics
Grantee:Viviane Oliveira Soares
Support type: Scholarships in Brazil - Post-Doctorate