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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effectiveness and acid/tooth brushing resistance of in-office desensitizing treatments-A hydraulic conductance study

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Joao-Souza, Samira Helena [1, 2] ; Machado, Alana Cristina [1] ; Lopes, Raquel Marianna [1] ; Zezell, Denise Maria [3] ; Scaramucci, Tais [1] ; Correa Aranha, Ana Cecilia [1]
Total Authors: 6
[1] Univ Sao Paulo, Sch Dent, Dept Restorat Dent, Ave Prof Lineu Prestes 2227, BR-05508000 Sao Paulo, SP - Brazil
[2] Univ Bern, Dept Restorat Prevent & Pediat Dent, Labor C331, Freiburgstr 7, CH-3010 Bern - Switzerland
[3] Univ Sao Paulo, IPEN CNEN, Inst Nucl Res IPEN, Ave Prof Lineu Prestes 2242, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: ARCHIVES OF ORAL BIOLOGY; v. 96, p. 130-136, DEC 2018.
Web of Science Citations: 2

Objective: To evaluate dentin permeability and tubule occlusion of in-office desensitizing treatments, and to analyze their resistance to erosive/abrasive challenges. Design: Ninety-one 1 mm-thick dentin discs were immersed in EDTA solution for 5 min. After analyzing the maximum dentin permeability, the specimens were randomly allocated into 7 experimental groups (n = 10): Control (no treatment); Er,Cr:YSGG laser; Nd:YAG laser; Gluma Desensitizer; Duraphat; Pro-Argin toothpaste; Calcium Sodium Phosphosilicate (CSP) paste. The post-treatment permeability was assessed and then the specimens were subjected to a 5-day erosion-abrasion cycling protocol: 4x/day of immersion in citric acid solution (5 min;0.3%), followed by exposure to clarified human saliva (60 min). After the first and last acid challenges, specimens were brushed for 15 s, with exposure to the toothpaste slurry for total time of 2 min. Dentin permeability was re-measured (post-cycling). Percentage of dentin permeability for each experimental time was calculated in relation to the maximum permeability (%Lp). Data were analyzed with 2-way repeated measures ANOVA and Tukey tests (alpha = 0.05). Surface modifications were analyzed by scanning electron microscopy. Results: In both experimental time CSP paste and Gluma Desensitizer did not differ from each other (p = 0.0874), and were the only groups that presented significantly lower %Lp than the Control (p = 0.026 and p = 0.022, respectively). After treatment, they were able to reduce dentin permeability in 82% and 72%, respectively. The %Lp post-cycling was higher than post-treatment value for all groups (p = 0.008). Dentin permeability increased 21% for CSP paste and 12% for Gluma, but they remained significant different from Control. Deposits on the surface were observed for CSP paste; and for Gluma, tubule diameters were shown to be smaller. Conclusions: CSP paste and Gluma Desensitizer were the only treatments able to decrease dentin permeability post-treatment and to sustain low permeability post-cycling. (AU)

FAPESP's process: 15/14117-2 - Hydraulic conductance and dentin tubular occlusion of different desensiting strategies for dentin hypersensitivity treatment
Grantee:Samira Helena João de Souza
Support Opportunities: Scholarships in Brazil - Doctorate