Data on IL-17 production induced by plant lectins

Author(s)

da Silva, Thiago Aparecido ^[1] ; Fernandes, Fabricio Freitas ^[1] ; Roque-Barreira, Maria Cristina ^[1]

Affiliation

^[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Biol Celulare & Mol & Bioagentes Patogen, Sao Paulo - Brazil

• Document type: Journal article
• Source: DATA IN BRIEF; v. 7, p. 1584-1587, JUN 2016.
• Web of Science Citations: 3

Abstract

We reported in article da Silva et al. (2016) {[}2] that ArtinM induces the IL-17 production through interaction with CD4(+) T cells and stimulation of IL-23 and IL-1. Besides ArtinM, other plant lectins (PLs) induce IL-17 production by murine spleen cells. The IL-17 production induced by PLs was evaluated regarding the involvement of IL-23, IL-6, Thl-, and Th2-cytokines. Furthermore, the effect exerted TLR2, TLR4, and CD14 on the PLs' performance in the induction of IL-17 was examined. The current data were compared to the known ArtinM ability to induce Th17 immunity. (C) 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (AU)

• FAPESP's process: 12/09611-0 - Effect of lectin ArtinM on murine CD4+ T and CD8+ T cells
• Grantee: Thiago Aparecido da Silva
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 13/04088-0 - Lectin from pathogens
• Grantee: Maria Cristina Roque Antunes Barreira
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 06/60642-2 - Lectins: biological effects and pharmaceutical applications
• Grantee: Maria Cristina Roque Antunes Barreira
• Support Opportunities: Research Projects - Thematic Grants