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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

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Pedroso, Tahisa Marcela [1] ; Van Schepdael, Ann [2] ; Nunes Salgado, Herida Regina [1]
Total Authors: 3
[1] Univ Estadual Paulista, UNESP, Fac Ciencias Farmaceut, Araraquara, SP - Brazil
[2] Univ Leuven, KU Leuven, Dept Pharmaceut & Pharmacol Sci, Pharmaceut Anal, Leuven - Belgium
Total Affiliations: 2
Document type: Journal article
Web of Science Citations: 0

An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10mM pH 7 and 15kV voltage, in the concentration range of 70 to 120gmL(-1). Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R-2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis. (AU)

FAPESP's process: 09/14825-6 - Pharmaceutical análisis of drugs and medicines: cefuroxime, teicoplanin and AZUMOLENE
Grantee:Hérida Regina Nunes Salgado
Support type: Regular Research Grants
FAPESP's process: 13/12959-0 - Development and validation of analytical methods for characterization and quantification of Ertapenem sodium in lyophilized powder for injectable solution
Grantee:Tahisa Marcela Pedroso
Support type: Scholarships in Brazil - Doctorate