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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Influence of sexual hormones on oxygen consumption in rats

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Author(s):
Filipe Fernandes Conti ; Iris Callado Sanches ; Nathalia Bernardes ; Guilherme Lemos Shimojo ; Diego Mendrot Taboas Figueroa ; Rogério Brandão Wichi ; Kátia De Angelis
Total Authors: 7
Document type: Journal article
Source: Revista Brasileira de Medicina do Esporte; v. 20, n. 6, p. -, Dez. 2014.
Abstract

Introduction: Literature findings suggest that fluctuations of female sex hormones may change the maximum oxygen consumption (VO2max).Objective:To compare the VO2max among male rats (M, n = 8), female rats on ovulatory (OV, n=8) or non-ovulatory (NOV, n=8) phases of the estrous cycle and ovariectomized (OS, n=8).Methods:The evaluation of oxygen consumption was performed on a treadmill coupled with metabolic box.Results: At rest VO2 was similar among groups. The M group had a higher VO2max compared to the NOV group, however showed similar values when compared to OV group. The VO2max was lower in the ovariectomized group (OS: 62±3 ml.kg-1.min-1) compared to other groups (M: 92±2; NOV: 77 ± 4; OV: 87 ± 3 ml.kg-1.min-1).Conclusions: These findings suggest that hormonal variation resulting from different phases of the estrous cycle and ovarian hormone deprivation can induce changes in maximal oxygen uptake in rats. (AU)

FAPESP's process: 12/20141-5 - Effects of aerobic,resistance or combined exercise training in experimental models of cardiometabolic disorders associated with ovarian hormone deprivation
Grantee:Kátia de Angelis Lobo D Avila
Support type: Regular Research Grants
FAPESP's process: 11/16441-0 - Effects of aerobic or resistance exercise training on autonomic parameters and oxidative stress in ovariectomized hypertensive rats
Grantee:Renata Kelly da Palma
Support type: Scholarships in Brazil - Master