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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

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Author(s):
Luís Fábio da Silva Batista ; Vânia Lúcia Ribeiro da Matta ; Thaise Yumie Tomokane ; Acácio Duarte Pacheco ; Fernando Tobias Silveira ; Claudio Nazaretian Rossi ; Mary Marcondes ; Márcia Dalastra Laurenti
Total Authors: 8
Document type: Journal article
Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 49, n. 3, p. -, Jun. 2016.
Abstract

Abstract: INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas. (AU)

FAPESP's process: 12/50285-9 - Clinical, immunological features and its correlation with genetic markers in canine visceral leishmaniasis
Grantee:Marcia Dalastra Laurenti
Support type: Regular Research Grants