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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Heterogeneity correction in the construction of optimized planning in radiotherapy using linear programming

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Author(s):
Rodrigo Sartorelo Salemi Viana ; Helenice de Oliveira Florentino ; Ernesto Augusto Bueno da Fonseca Lima ; Paulo Roberto da Fonseca ; Thiago Pedro Donadon Homem
Total Authors: 5
Document type: Journal article
Source: Pesquisa Operacional; v. 31, n. 3, p. -, Dez. 2011.
Abstract

A radiotherapy planning is considered optimal when all the parameters involved, physical or biological, have been investigated and appropriate for each patient. In this type of planning, the major concern is with the tumor irradiation with the minimum possible damage to healthy tissues of the irradiated region, especially the organs at risk. The optimal planning for radiotherapy can be aided by Linear Programming and there is a wide literature addressing this subject. However, most published mathematical formulations do not contemplate a scenario in terms of practical applications, because they do not incorporate the heterogeneous composition of the irradiated tissue. This paper presents a methodology for heterogeneity correction in the composition of different types of irradiated tissues based on proportions among their different linear attenuation coefficient. (AU)

FAPESP's process: 06/02476-9 - Mathematical programming in the exploitation of sugarcane harvest residual biomass
Grantee:Helenice de Oliveira Florentino Silva
Support type: Regular Research Grants
FAPESP's process: 07/02313-5 - Theoretical and experimental modeling for ACB optimization: a new methodology for quality control in solid dosage forms disintegration
Grantee:Paulo Roberto da Fonseca Filho
Support type: Scholarships in Brazil - Master