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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Neuroimmunomodulation: the cross-talk between nervous and immune systems

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Glaucie Jussilane Alves ; João Palermo-Neto
Total Authors: 2
Document type: Journal article
Source: Revista Brasileira de Psiquiatria; v. 29, n. 4, p. -, Dez. 2007.

OBJECTIVE: Several papers arriving from the neuroimmunomodulation field are showing the relevant relationships between the nervous and the immune systems. A review of studies was carried out to describe the bases of the studies on neuroimmunomodulation. EXPERIMENTAL MODELS: It is clear nowadays that emotional states such as anxiety and depression change immune system activity, an affect also observed after both stress and use of nervous system acting drugs. SICK BEHAVIOR: The behavior displayed by sick organisms might be thought as being a consequence of homeostatic strategies. POSSIBLE MECHANISM OF THE ACTION BY MEANS OF IMMUNE SYSTEM TO NERVOUS SYSTEM: A very big emphasis is being given to Hipothalamus-pituitary-adrenal axis, simpathetic nervous system and cytokines participation on nervous system and immune system relationships. CONCLUSION: The present revision intend to show some essential studies in the neuroimmunomodulation field; it makes a critical analysis of the mutual relationships between nervous system and immune system. (AU)

FAPESP's process: 04/14128-0 - Neuroimmunomodulation: effects of drugs, stress and cytocines on central nervous and immune systems bidirectional relationships
Grantee:João Palermo Neto
Support type: Research Projects - Thematic Grants
FAPESP's process: 99/04228-7 - Neuroimmunomodulation: effects of stress and central nervous system acting drugs on immune/inflamatory response
Grantee:João Palermo Neto
Support type: Research Projects - Thematic Grants